G721-0329 Screening compound: 2-{[1,3-dimethyl-6-(2-methylpropyl)-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-5-yl]sulfanyl}-N-(2,5-dimethylphenyl)acetamide

G721-0329 Screening compound: 2-{[1,3-dimethyl-6-(2-methylpropyl)-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-5-yl]sulfanyl}-N-(2,5-dimethylphenyl)acetamide
G721-0329 Screening compound: 2-{[1,3-dimethyl-6-(2-methylpropyl)-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-5-yl]sulfanyl}-N-(2,5-dimethylphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G721-0329
2-{[1,3-dimethyl-6-(2-methylpropyl)-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-5-yl]sulfanyl}-N-(2,5-dimethylphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G721-0329

Molecular Formula

C23H28N4O3S (C23 H28 N4 O3 S)

Compound Name

2-{[1,3-dimethyl-6-(2-methylpropyl)-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-5-yl]sulfanyl}-N-(2,5-dimethylphenyl)acetamide

IUPAC name

2-{[13-dimethyl-6-(2-methylpropyl)-24-dioxo-1H2H3H4H-pyrido[23-d]pyrimidin-5-yl]sulfanyl}-N-(25-dimethylphenyl)acetamide

SMILES

CC(C)Cc(c(SCC(Nc1c(C)ccc(C)c1)=O)c1C(N2C)=O)cnc1N(C)C2=O

InChI

InChI=1S/C23H28N4O3S/c1-13(2)9-16-11-24-21-19(22(29)27(6)23(30)26(21)5)20(16)31-12-18(28)25-17-10-14(3)7-8-15(17)4/h7-8,10-11,13H,9,12H2,1-6H3,(H,25,28)

InChI Key

GCSIMUXFLDXNMI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08326516

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

440.57

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.869

Distribution Coefficient, logD

3.869

Water Solubility, LogSw

-3.91

Polar Surface Area

63.942

Acid Dissociation Constant (pKa)

12.70

Base Dissociation Constant (pKb)

3.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.10

G721-0329 in Drug Discovery

Included in Screening Libraries

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G721-0329 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G721-0329?
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What is the minimum amount of G721-0329 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G721-0329
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G721-0329
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G721-0329 available by request