G721-0408 Screening compound: benzyl 2-{[1,3-dimethyl-6-(2-methylpropyl)-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-5-yl]sulfanyl}acetate

G721-0408 Screening compound: benzyl 2-{[1,3-dimethyl-6-(2-methylpropyl)-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-5-yl]sulfanyl}acetate
G721-0408 Screening compound: benzyl 2-{[1,3-dimethyl-6-(2-methylpropyl)-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-5-yl]sulfanyl}acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound G721-0408
benzyl 2-{[1,3-dimethyl-6-(2-methylpropyl)-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-5-yl]sulfanyl}acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G721-0408

Molecular Formula

C22H25N3O4S (C22 H25 N3 O4 S)

Compound Name

benzyl 2-{[1,3-dimethyl-6-(2-methylpropyl)-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-5-yl]sulfanyl}acetate

IUPAC name

benzyl 2-{[13-dimethyl-6-(2-methylpropyl)-24-dioxo-1H2H3H4H-pyrido[23-d]pyrimidin-5-yl]sulfanyl}acetate

SMILES

CC(C)Cc(c(SCC(OCc1ccccc1)=O)c1C(N2C)=O)cnc1N(C)C2=O

InChI

InChI=1S/C22H25N3O4S/c1-14(2)10-16-11-23-20-18(21(27)25(4)22(28)24(20)3)19(16)30-13-17(26)29-12-15-8-6-5-7-9-15/h5-9,11,14H,10,12-13H2,1-4H3

InChI Key

IREUIXADWFDKPH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08326595

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

427.52

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.309

Distribution Coefficient, logD

4.309

Water Solubility, LogSw

-4.53

Polar Surface Area

62.024

Acid Dissociation Constant (pKa)

22.80

Base Dissociation Constant (pKb)

3.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

G721-0408 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G721-0408 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G721-0408?
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What is the minimum amount of G721-0408 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G721-0408
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G721-0408
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G721-0408 available by request