G729-1277 Screening compound: 3-(3-{[(4-FLUOROPHENYL)SULFONYL]METHYL}-1,2,4-OXADIAZOL-5-YL)-1-MORPHOLINO-1-PROPANONE

G729-1277 Screening compound: 3-(3-{[(4-FLUOROPHENYL)SULFONYL]METHYL}-1,2,4-OXADIAZOL-5-YL)-1-MORPHOLINO-1-PROPANONE
G729-1277 Screening compound: 3-(3-{[(4-FLUOROPHENYL)SULFONYL]METHYL}-1,2,4-OXADIAZOL-5-YL)-1-MORPHOLINO-1-PROPANONE alternative view

Chemical Structure Depiction of ChemDiv screening compound G729-1277
3-(3-{[(4-FLUOROPHENYL)SULFONYL]METHYL}-1,2,4-OXADIAZOL-5-YL)-1-MORPHOLINO-1-PROPANONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G729-1277

Molecular Formula

C16H18FN3O5S (C16 H18 FN3 O5 S)

Compound Name

3-(3-{[(4-FLUOROPHENYL)SULFONYL]METHYL}-1,2,4-OXADIAZOL-5-YL)-1-MORPHOLINO-1-PROPANONE

IUPAC name

3-{3-[(4-fluorobenzenesulfonyl)methyl]-124-oxadiazol-5-yl}-1-(morpholin-4-yl)propan-1-one

SMILES

O=C(CCc1nc(CS(c(cc2)ccc2F)(=O)=O)no1)N1CCOCC1

InChI

InChI=1S/C16H18FN3O5S/c17-12-1-3-13(4-2-12)26(22,23)11-14-18-15(25-19-14)5-6-16(21)20-7-9-24-10-8-20/h1-4H,5-11H2

InChI Key

HIWDFKZZYOQOCG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27154618

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

383.4

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

0.547

Distribution Coefficient, logD

0.547

Water Solubility, LogSw

-2.16

Polar Surface Area

85.638

Acid Dissociation Constant (pKa)

23.79

Base Dissociation Constant (pKb)

-1.42

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

43.75

G729-1277 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G729-1277 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G729-1277?
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What is the minimum amount of G729-1277 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G729-1277
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G729-1277
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G729-1277 available by request