G732-2774 Screening compound: 1-benzyl-5-(dimethylsulfamoyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1H-indole-2-carboxamide

G732-2774 Screening compound: 1-benzyl-5-(dimethylsulfamoyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1H-indole-2-carboxamide
G732-2774 Screening compound: 1-benzyl-5-(dimethylsulfamoyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1H-indole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G732-2774
1-benzyl-5-(dimethylsulfamoyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1H-indole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G732-2774

Molecular Formula

C28H29N3O3S (C28 H29 N3 O3 S)

Compound Name

1-benzyl-5-(dimethylsulfamoyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1H-indole-2-carboxamide

IUPAC name

1-benzyl-5-(dimethylsulfamoyl)-N-(1234-tetrahydronaphthalen-1-yl)-1H-indole-2-carboxamide

SMILES

CN(C)S(c(cc1)cc2c1n(Cc1ccccc1)c(C(NC(CCC1)c3c1cccc3)=O)c2)(=O)=O

InChI

InChI=1S/C28H29N3O3S/c1-30(2)35(33,34)23-15-16-26-22(17-23)18-27(31(26)19-20-9-4-3-5-10-20)28(32)29-25-14-8-12-21-11-6-7-13-24(21)25/h3-7,9-11,13,15-18,25H,8,12,14,19H2,1-2H3,(H,29,32)/t25-/m0/s1

InChI Key

FIRVQDJCOJQGBH-VWLOTQADSA-N

MDL Number (MFCD)

MFCD27154928

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

487.62

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.271

Distribution Coefficient, logD

5.271

Water Solubility, LogSw

-5.31

Polar Surface Area

58.613

Acid Dissociation Constant (pKa)

11.52

Base Dissociation Constant (pKb)

-2.28

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

25.00

G732-2774 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G732-2774 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G732-2774?
Check Price and Availability of G732-2774, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G732-2774 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G732-2774
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G732-2774
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G732-2774 available by request