G732-3637 Screening compound: 5-(dimethylsulfamoyl)-1-[(pyridin-4-yl)methyl]-N-[2-(thiophen-2-yl)ethyl]-1H-indole-2-carboxamide

G732-3637 Screening compound: 5-(dimethylsulfamoyl)-1-[(pyridin-4-yl)methyl]-N-[2-(thiophen-2-yl)ethyl]-1H-indole-2-carboxamide
G732-3637 Screening compound: 5-(dimethylsulfamoyl)-1-[(pyridin-4-yl)methyl]-N-[2-(thiophen-2-yl)ethyl]-1H-indole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G732-3637
5-(dimethylsulfamoyl)-1-[(pyridin-4-yl)methyl]-N-[2-(thiophen-2-yl)ethyl]-1H-indole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G732-3637

Molecular Formula

C23H24N4O3S2 (C23 H24 N4 O3 S2)

Compound Name

5-(dimethylsulfamoyl)-1-[(pyridin-4-yl)methyl]-N-[2-(thiophen-2-yl)ethyl]-1H-indole-2-carboxamide

IUPAC name

5-(dimethylsulfamoyl)-1-[(pyridin-4-yl)methyl]-N-[2-(thiophen-2-yl)ethyl]-1H-indole-2-carboxamide

SMILES

CN(C)S(c(cc1)cc2c1n(Cc1ccncc1)c(C(NCCc1cccs1)=O)c2)(=O)=O

InChI

InChI=1S/C23H24N4O3S2/c1-26(2)32(29,30)20-5-6-21-18(14-20)15-22(27(21)16-17-7-10-24-11-8-17)23(28)25-12-9-19-4-3-13-31-19/h3-8,10-11,13-15H,9,12,16H2,1-2H3,(H,25,28)

InChI Key

SXYYTIOYQHNGQJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27155066

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

468.6

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.859

Distribution Coefficient, logD

2.858

Water Solubility, LogSw

-3.25

Polar Surface Area

69.058

Acid Dissociation Constant (pKa)

14.01

Base Dissociation Constant (pKb)

3.34

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

G732-3637 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

KRAS-Targeted Library (16000 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G732-3637 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G732-3637?
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What is the minimum amount of G732-3637 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G732-3637
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G732-3637
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G732-3637 available by request