G740-0860 Screening compound: 5-{2-[4-(furan-2-carbonyl)piperazin-1-yl]-2-oxoethyl}-3,7-dimethyl-2-phenyl-2H,4H,5H-pyrazolo[3,4-d]pyridazin-4-one

G740-0860 Screening compound: 5-{2-[4-(furan-2-carbonyl)piperazin-1-yl]-2-oxoethyl}-3,7-dimethyl-2-phenyl-2H,4H,5H-pyrazolo[3,4-d]pyridazin-4-one
G740-0860 Screening compound: 5-{2-[4-(furan-2-carbonyl)piperazin-1-yl]-2-oxoethyl}-3,7-dimethyl-2-phenyl-2H,4H,5H-pyrazolo[3,4-d]pyridazin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G740-0860
5-{2-[4-(furan-2-carbonyl)piperazin-1-yl]-2-oxoethyl}-3,7-dimethyl-2-phenyl-2H,4H,5H-pyrazolo[3,4-d]pyridazin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G740-0860

Molecular Formula

C24H24N6O4 (C24 H24 N6 O4)

Compound Name

5-{2-[4-(furan-2-carbonyl)piperazin-1-yl]-2-oxoethyl}-3,7-dimethyl-2-phenyl-2H,4H,5H-pyrazolo[3,4-d]pyridazin-4-one

IUPAC name

5-{2-[4-(furan-2-carbonyl)piperazin-1-yl]-2-oxoethyl}-37-dimethyl-2-phenyl-2H4H5H-pyrazolo[34-d]pyridazin-4-one

SMILES

Cc(n(-c1ccccc1)nc1C(C)=NN2CC(N(CC3)CCN3C(c3ccco3)=O)=O)c1C2=O

InChI

InChI=1S/C24H24N6O4/c1-16-22-21(17(2)30(26-22)18-7-4-3-5-8-18)24(33)29(25-16)15-20(31)27-10-12-28(13-11-27)23(32)19-9-6-14-34-19/h3-9,14H,10-13,15H2,1-2H3

InChI Key

JEEKLCOIHKETJB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15030979

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

460.49

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.022

Distribution Coefficient, logD

1.022

Water Solubility, LogSw

-1.85

Polar Surface Area

82.769

Acid Dissociation Constant (pKa)

16.35

Base Dissociation Constant (pKb)

1.16

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

G740-0860 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G740-0860 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G740-0860?
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What is the minimum amount of G740-0860 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G740-0860
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G740-0860
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G740-0860 available by request