G740-1218 Screening compound: 3,7-DIMETHYL-5-[1-OXO-1-(4-PROPYLPIPERAZIN-1-YL)BUTAN-2-YL]-2-PHENYL-2H,4H,5H-PYRAZOLO[3,4-D]PYRIDAZIN-4-ONE

G740-1218 Screening compound: 3,7-DIMETHYL-5-[1-OXO-1-(4-PROPYLPIPERAZIN-1-YL)BUTAN-2-YL]-2-PHENYL-2H,4H,5H-PYRAZOLO[3,4-D]PYRIDAZIN-4-ONE
G740-1218 Screening compound: 3,7-DIMETHYL-5-[1-OXO-1-(4-PROPYLPIPERAZIN-1-YL)BUTAN-2-YL]-2-PHENYL-2H,4H,5H-PYRAZOLO[3,4-D]PYRIDAZIN-4-ONE alternative view

Chemical Structure Depiction of ChemDiv screening compound G740-1218
3,7-DIMETHYL-5-[1-OXO-1-(4-PROPYLPIPERAZIN-1-YL)BUTAN-2-YL]-2-PHENYL-2H,4H,5H-PYRAZOLO[3,4-D]PYRIDAZIN-4-ONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G740-1218

Molecular Formula

C24H32N6O2 (C24 H32 N6 O2)

Compound Name

3,7-DIMETHYL-5-[1-OXO-1-(4-PROPYLPIPERAZIN-1-YL)BUTAN-2-YL]-2-PHENYL-2H,4H,5H-PYRAZOLO[3,4-D]PYRIDAZIN-4-ONE

IUPAC name

n/a

SMILES

CCCN(CC1)CCN1C(C(CC)N(C(c1c2C)=O)N=C(C)c1nn2-c1ccccc1)=O

InChI

InChI=1S/C24H32N6O2/c1-5-12-27-13-15-28(16-14-27)23(31)20(6-2)30-24(32)21-18(4)29(19-10-8-7-9-11-19)26-22(21)17(3)25-30/h7-11,20H,5-6,12-16H2,1-4H3/t20-/m0/s1

InChI Key

JIQVYYLPMCMIJQ-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD27155179

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

436.56

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.778

Distribution Coefficient, logD

2.513

Water Solubility, LogSw

-2.88

Polar Surface Area

60.170

Acid Dissociation Constant (pKa)

14.71

Base Dissociation Constant (pKb)

7.32

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

50.00

G740-1218 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G740-1218 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G740-1218?
Check Price and Availability of G740-1218, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G740-1218 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G740-1218
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G740-1218
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G740-1218 available by request