G740-1257 Screening compound: N-(2-chloro-4-fluorophenyl)-2-{3,7-dimethyl-4-oxo-2-phenyl-2H,4H,5H-pyrazolo[3,4-d]pyridazin-5-yl}butanamide

G740-1257 Screening compound: N-(2-chloro-4-fluorophenyl)-2-{3,7-dimethyl-4-oxo-2-phenyl-2H,4H,5H-pyrazolo[3,4-d]pyridazin-5-yl}butanamide
G740-1257 Screening compound: N-(2-chloro-4-fluorophenyl)-2-{3,7-dimethyl-4-oxo-2-phenyl-2H,4H,5H-pyrazolo[3,4-d]pyridazin-5-yl}butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G740-1257
N-(2-chloro-4-fluorophenyl)-2-{3,7-dimethyl-4-oxo-2-phenyl-2H,4H,5H-pyrazolo[3,4-d]pyridazin-5-yl}butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G740-1257

Molecular Formula

C23H21ClFN5O2 (C23 H21 ClFN5 O2)

Compound Name

N-(2-chloro-4-fluorophenyl)-2-{3,7-dimethyl-4-oxo-2-phenyl-2H,4H,5H-pyrazolo[3,4-d]pyridazin-5-yl}butanamide

IUPAC name

N-(2-chloro-4-fluorophenyl)-2-{37-dimethyl-4-oxo-2-phenyl-2H4H5H-pyrazolo[34-d]pyridazin-5-yl}butanamide

SMILES

CCC(C(Nc(ccc(F)c1)c1Cl)=O)N(C(c1c2C)=O)N=C(C)c1nn2-c1ccccc1

InChI

InChI=1S/C23H21ClFN5O2/c1-4-19(22(31)26-18-11-10-15(25)12-17(18)24)30-23(32)20-14(3)29(16-8-6-5-7-9-16)28-21(20)13(2)27-30/h5-12,19H,4H2,1-3H3,(H,26,31)/t19-/m0/s1

InChI Key

RPANKFLPADRAAQ-IBGZPJMESA-N

MDL Number (MFCD)

MFCD27155198

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

453.9

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.541

Distribution Coefficient, logD

4.531

Water Solubility, LogSw

-4.75

Polar Surface Area

62.125

Acid Dissociation Constant (pKa)

9.01

Base Dissociation Constant (pKb)

0.09

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

21.70

G740-1257 in Drug Discovery

Included in Screening Libraries

Neuropeptide S Library (2850 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Nervous system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G740-1257 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G740-1257?
Check Price and Availability of G740-1257, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G740-1257 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G740-1257
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G740-1257
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G740-1257 available by request