G741-1275 Screening compound: N-(4-fluorophenyl)-4-({[(3-methoxyphenyl)methyl]carbamoyl}methyl)-3-oxo-1,2,3,4-tetrahydroquinoxaline-1-carboxamide

G741-1275 Screening compound: N-(4-fluorophenyl)-4-({[(3-methoxyphenyl)methyl]carbamoyl}methyl)-3-oxo-1,2,3,4-tetrahydroquinoxaline-1-carboxamide
G741-1275 Screening compound: N-(4-fluorophenyl)-4-({[(3-methoxyphenyl)methyl]carbamoyl}methyl)-3-oxo-1,2,3,4-tetrahydroquinoxaline-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G741-1275
N-(4-fluorophenyl)-4-({[(3-methoxyphenyl)methyl]carbamoyl}methyl)-3-oxo-1,2,3,4-tetrahydroquinoxaline-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G741-1275

Molecular Formula

C25H23FN4O4 (C25 H23 FN4 O4)

Compound Name

N-(4-fluorophenyl)-4-({[(3-methoxyphenyl)methyl]carbamoyl}methyl)-3-oxo-1,2,3,4-tetrahydroquinoxaline-1-carboxamide

IUPAC name

N-(4-fluorophenyl)-4-({[(3-methoxyphenyl)methyl]carbamoyl}methyl)-3-oxo-1234-tetrahydroquinoxaline-1-carboxamide

SMILES

COc1cccc(CNC(CN(C(C2)=O)c(cccc3)c3N2C(Nc(cc2)ccc2F)=O)=O)c1

InChI

InChI=1S/C25H23FN4O4/c1-34-20-6-4-5-17(13-20)14-27-23(31)15-29-21-7-2-3-8-22(21)30(16-24(29)32)25(33)28-19-11-9-18(26)10-12-19/h2-13H,14-16H2,1H3,(H,27,31)(H,28,33)

InChI Key

KMAKSENYDJHZQC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27155423

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

462.48

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.140

Distribution Coefficient, logD

3.140

Water Solubility, LogSw

-3.51

Polar Surface Area

71.781

Acid Dissociation Constant (pKa)

12.73

Base Dissociation Constant (pKb)

0.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.00

G741-1275 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G741-1275 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G741-1275?
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What is the minimum amount of G741-1275 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G741-1275
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G741-1275
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G741-1275 available by request