G741-1614 Screening compound: 4-[2-(4-carbamoylpiperidin-1-yl)-2-oxoethyl]-N-(4-ethoxyphenyl)-3-oxo-1,2,3,4-tetrahydroquinoxaline-1-carboxamide

G741-1614 Screening compound: 4-[2-(4-carbamoylpiperidin-1-yl)-2-oxoethyl]-N-(4-ethoxyphenyl)-3-oxo-1,2,3,4-tetrahydroquinoxaline-1-carboxamide
G741-1614 Screening compound: 4-[2-(4-carbamoylpiperidin-1-yl)-2-oxoethyl]-N-(4-ethoxyphenyl)-3-oxo-1,2,3,4-tetrahydroquinoxaline-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G741-1614
4-[2-(4-carbamoylpiperidin-1-yl)-2-oxoethyl]-N-(4-ethoxyphenyl)-3-oxo-1,2,3,4-tetrahydroquinoxaline-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G741-1614

Molecular Formula

C25H29N5O5 (C25 H29 N5 O5)

Compound Name

4-[2-(4-carbamoylpiperidin-1-yl)-2-oxoethyl]-N-(4-ethoxyphenyl)-3-oxo-1,2,3,4-tetrahydroquinoxaline-1-carboxamide

IUPAC name

4-[2-(4-carbamoylpiperidin-1-yl)-2-oxoethyl]-N-(4-ethoxyphenyl)-3-oxo-1234-tetrahydroquinoxaline-1-carboxamide

SMILES

CCOc(cc1)ccc1NC(N(C1)c(cccc2)c2N(CC(N(CC2)CCC2C(N)=O)=O)C1=O)=O

InChI

InChI=1S/C25H29N5O5/c1-2-35-19-9-7-18(8-10-19)27-25(34)30-16-23(32)29(20-5-3-4-6-21(20)30)15-22(31)28-13-11-17(12-14-28)24(26)33/h3-10,17H,2,11-16H2,1H3,(H2,26,33)(H,27,34)

InChI Key

NCMAXSPGTCYIGC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27155470

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

479.54

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.113

Distribution Coefficient, logD

1.113

Water Solubility, LogSw

-2.18

Polar Surface Area

97.340

Acid Dissociation Constant (pKa)

14.20

Base Dissociation Constant (pKb)

2.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.00

G741-1614 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with G741-1614 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G741-1614?
Check Price and Availability of G741-1614, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G741-1614 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G741-1614
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G741-1614
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G741-1614 available by request