G743-0408 Screening compound: 3-(4-{[4-(3-methylphenyl)piperazino]carbonyl}phenyl)-3,4-dihydro-1lambda~6~,2,4-benzothiadiazine-1,1(2H)-dione

G743-0408 Screening compound: 3-(4-{[4-(3-methylphenyl)piperazino]carbonyl}phenyl)-3,4-dihydro-1lambda~6~,2,4-benzothiadiazine-1,1(2H)-dione
G743-0408 Screening compound: 3-(4-{[4-(3-methylphenyl)piperazino]carbonyl}phenyl)-3,4-dihydro-1lambda~6~,2,4-benzothiadiazine-1,1(2H)-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound G743-0408
3-(4-{[4-(3-methylphenyl)piperazino]carbonyl}phenyl)-3,4-dihydro-1lambda~6~,2,4-benzothiadiazine-1,1(2H)-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G743-0408

Molecular Formula

C25H26N4O3S (C25 H26 N4 O3 S)

Compound Name

3-(4-{[4-(3-methylphenyl)piperazino]carbonyl}phenyl)-3,4-dihydro-1lambda~6~,2,4-benzothiadiazine-1,1(2H)-dione

IUPAC name

3-{4-[4-(3-methylphenyl)piperazine-1-carbonyl]phenyl}-34-dihydro-2H-1lambda624-benzothiadiazine-11-dione

SMILES

Cc1cccc(N(CC2)CCN2C(c2ccc(C(Nc3c4cccc3)NS4(=O)=O)cc2)=O)c1

InChI

InChI=1S/C25H26N4O3S/c1-18-5-4-6-21(17-18)28-13-15-29(16-14-28)25(30)20-11-9-19(10-12-20)24-26-22-7-2-3-8-23(22)33(31,32)27-24/h2-12,17,24,26-27H,13-16H2,1H3/t24-/m0/s1

InChI Key

CREWCJYLEAADQE-DEOSSOPVSA-N

MDL Number (MFCD)

MFCD27155522

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

462.57

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.850

Distribution Coefficient, logD

2.850

Water Solubility, LogSw

-3.46

Polar Surface Area

72.009

Acid Dissociation Constant (pKa)

10.76

Base Dissociation Constant (pKb)

2.02

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

24.00

G743-0408 in Drug Discovery

Included in Screening Libraries

RNA-Protein Interaction Inhibitors Library (1986 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G743-0408 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G743-0408?
Check Price and Availability of G743-0408, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G743-0408 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G743-0408
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G743-0408
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G743-0408 available by request