G747-0106 Screening compound: 4-hydroxy-1-[(4-methoxyphenyl)methyl]-6-methyl-3-{phenyl[4-(pyridin-2-yl)piperazin-1-yl]methyl}-1,2-dihydropyridin-2-one

G747-0106 Screening compound: 4-hydroxy-1-[(4-methoxyphenyl)methyl]-6-methyl-3-{phenyl[4-(pyridin-2-yl)piperazin-1-yl]methyl}-1,2-dihydropyridin-2-one
G747-0106 Screening compound: 4-hydroxy-1-[(4-methoxyphenyl)methyl]-6-methyl-3-{phenyl[4-(pyridin-2-yl)piperazin-1-yl]methyl}-1,2-dihydropyridin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G747-0106
4-hydroxy-1-[(4-methoxyphenyl)methyl]-6-methyl-3-{phenyl[4-(pyridin-2-yl)piperazin-1-yl]methyl}-1,2-dihydropyridin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G747-0106

Molecular Formula

C30H32N4O3 (C30 H32 N4 O3)

Compound Name

4-hydroxy-1-[(4-methoxyphenyl)methyl]-6-methyl-3-{phenyl[4-(pyridin-2-yl)piperazin-1-yl]methyl}-1,2-dihydropyridin-2-one

IUPAC name

4-hydroxy-1-[(4-methoxyphenyl)methyl]-6-methyl-3-{phenyl[4-(pyridin-2-yl)piperazin-1-yl]methyl}-12-dihydropyridin-2-one

SMILES

CC(N1Cc(cc2)ccc2OC)=CC(O)=C(C(c2ccccc2)N(CC2)CCN2c2ncccc2)C1=O

InChI

InChI=1S/C30H32N4O3/c1-22-20-26(35)28(30(36)34(22)21-23-11-13-25(37-2)14-12-23)29(24-8-4-3-5-9-24)33-18-16-32(17-19-33)27-10-6-7-15-31-27/h3-15,20,29,35H,16-19,21H2,1-2H3/t29-/m0/s1

InChI Key

MQMGXGAMHBDRSE-LJAQVGFWSA-N

MDL Number (MFCD)

MFCD09237468

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

496.61

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.885

Distribution Coefficient, logD

2.977

Water Solubility, LogSw

-4.39

Polar Surface Area

52.673

Acid Dissociation Constant (pKa)

5.50

Base Dissociation Constant (pKb)

6.09

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

26.70

G747-0106 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G747-0106 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G747-0106?
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What is the minimum amount of G747-0106 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G747-0106
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G747-0106
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G747-0106 available by request