G747-0303 Screening compound: 3-[(3-chlorophenyl)(4-methylpiperidin-1-yl)methyl]-4-hydroxy-1-(2-methoxyethyl)-6-methyl-1,2-dihydropyridin-2-one

G747-0303 Screening compound: 3-[(3-chlorophenyl)(4-methylpiperidin-1-yl)methyl]-4-hydroxy-1-(2-methoxyethyl)-6-methyl-1,2-dihydropyridin-2-one
G747-0303 Screening compound: 3-[(3-chlorophenyl)(4-methylpiperidin-1-yl)methyl]-4-hydroxy-1-(2-methoxyethyl)-6-methyl-1,2-dihydropyridin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G747-0303
3-[(3-chlorophenyl)(4-methylpiperidin-1-yl)methyl]-4-hydroxy-1-(2-methoxyethyl)-6-methyl-1,2-dihydropyridin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G747-0303

Molecular Formula

C22H29ClN2O3 (C22 H29 ClN2 O3)

Compound Name

3-[(3-chlorophenyl)(4-methylpiperidin-1-yl)methyl]-4-hydroxy-1-(2-methoxyethyl)-6-methyl-1,2-dihydropyridin-2-one

IUPAC name

3-[(3-chlorophenyl)(4-methylpiperidin-1-yl)methyl]-4-hydroxy-1-(2-methoxyethyl)-6-methyl-12-dihydropyridin-2-one

SMILES

CC(CC1)CCN1C(c1cccc(Cl)c1)C(C(N(CCOC)C(C)=C1)=O)=C1O

InChI

InChI=1S/C22H29ClN2O3/c1-15-7-9-24(10-8-15)21(17-5-4-6-18(23)14-17)20-19(26)13-16(2)25(22(20)27)11-12-28-3/h4-6,13-15,21,26H,7-12H2,1-3H3/t21-/m0/s1

InChI Key

ZEQNIIMYVLUAGM-NRFANRHFSA-N

MDL Number (MFCD)

MFCD09237586

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

404.94

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.714

Distribution Coefficient, logD

3.714

Water Solubility, LogSw

-3.93

Polar Surface Area

41.950

Acid Dissociation Constant (pKa)

5.85

Base Dissociation Constant (pKb)

8.64

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

50.00

G747-0303 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with G747-0303 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G747-0303?
Check Price and Availability of G747-0303, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G747-0303 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G747-0303
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G747-0303
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G747-0303 available by request