G747-0359 Screening compound: 4-hydroxy-1-(2-methoxyethyl)-6-methyl-3-[(4-phenylpiperazin-1-yl)(pyridin-3-yl)methyl]-1,2-dihydropyridin-2-one

G747-0359 Screening compound: 4-hydroxy-1-(2-methoxyethyl)-6-methyl-3-[(4-phenylpiperazin-1-yl)(pyridin-3-yl)methyl]-1,2-dihydropyridin-2-one
G747-0359 Screening compound: 4-hydroxy-1-(2-methoxyethyl)-6-methyl-3-[(4-phenylpiperazin-1-yl)(pyridin-3-yl)methyl]-1,2-dihydropyridin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G747-0359
4-hydroxy-1-(2-methoxyethyl)-6-methyl-3-[(4-phenylpiperazin-1-yl)(pyridin-3-yl)methyl]-1,2-dihydropyridin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G747-0359

Molecular Formula

C25H30N4O3 (C25 H30 N4 O3)

Compound Name

4-hydroxy-1-(2-methoxyethyl)-6-methyl-3-[(4-phenylpiperazin-1-yl)(pyridin-3-yl)methyl]-1,2-dihydropyridin-2-one

IUPAC name

4-hydroxy-1-(2-methoxyethyl)-6-methyl-3-[(4-phenylpiperazin-1-yl)(pyridin-3-yl)methyl]-12-dihydropyridin-2-one

SMILES

CC(N1CCOC)=CC(O)=C(C(c2cnccc2)N(CC2)CCN2c2ccccc2)C1=O

InChI

InChI=1S/C25H30N4O3/c1-19-17-22(30)23(25(31)29(19)15-16-32-2)24(20-7-6-10-26-18-20)28-13-11-27(12-14-28)21-8-4-3-5-9-21/h3-10,17-18,24,30H,11-16H2,1-2H3/t24-/m0/s1

InChI Key

LCYOXWOPQCQHTG-DEOSSOPVSA-N

MDL Number (MFCD)

MFCD09237610

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

434.54

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.286

Distribution Coefficient, logD

0.687

Water Solubility, LogSw

-1.95

Polar Surface Area

54.728

Acid Dissociation Constant (pKa)

5.81

Base Dissociation Constant (pKb)

5.69

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

36.00

G747-0359 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G747-0359 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G747-0359?
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What is the minimum amount of G747-0359 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G747-0359
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G747-0359
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G747-0359 available by request