G748-0006 Screening compound: N-[4-carbamoyl-2-(ethylamino)-1,3-thiazol-5-yl]-2-(3,4-dimethylphenyl)quinoline-4-carboxamide

G748-0006 Screening compound: N-[4-carbamoyl-2-(ethylamino)-1,3-thiazol-5-yl]-2-(3,4-dimethylphenyl)quinoline-4-carboxamide
G748-0006 Screening compound: N-[4-carbamoyl-2-(ethylamino)-1,3-thiazol-5-yl]-2-(3,4-dimethylphenyl)quinoline-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G748-0006
N-[4-carbamoyl-2-(ethylamino)-1,3-thiazol-5-yl]-2-(3,4-dimethylphenyl)quinoline-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G748-0006

Molecular Formula

C24H23N5O2S (C24 H23 N5 O2 S)

Compound Name

N-[4-carbamoyl-2-(ethylamino)-1,3-thiazol-5-yl]-2-(3,4-dimethylphenyl)quinoline-4-carboxamide

IUPAC name

N-[4-carbamoyl-2-(ethylamino)-13-thiazol-5-yl]-2-(34-dimethylphenyl)quinoline-4-carboxamide

SMILES

CCNc1nc(C(N)=O)c(NC(c2cc(-c3cc(C)c(C)cc3)nc3ccccc23)=O)s1

InChI

InChI=1S/C24H23N5O2S/c1-4-26-24-28-20(21(25)30)23(32-24)29-22(31)17-12-19(15-10-9-13(2)14(3)11-15)27-18-8-6-5-7-16(17)18/h5-12H,4H2,1-3H3,(H2,25,30)(H,26,28)(H,29,31)

InChI Key

XYTHXUSOGRYVRP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27155669

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.55

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.029

Distribution Coefficient, logD

5.027

Water Solubility, LogSw

-4.88

Polar Surface Area

85.172

Acid Dissociation Constant (pKa)

9.77

Base Dissociation Constant (pKb)

2.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

G748-0006 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with G748-0006 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G748-0006?
Check Price and Availability of G748-0006, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G748-0006 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G748-0006
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G748-0006
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G748-0006 available by request