G748-0169 Screening compound: 5-(4-acetamidobenzamido)-2-[(4-methylphenyl)amino]-1,3-thiazole-4-carboxamide

G748-0169 Screening compound: 5-(4-acetamidobenzamido)-2-[(4-methylphenyl)amino]-1,3-thiazole-4-carboxamide
G748-0169 Screening compound: 5-(4-acetamidobenzamido)-2-[(4-methylphenyl)amino]-1,3-thiazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G748-0169
5-(4-acetamidobenzamido)-2-[(4-methylphenyl)amino]-1,3-thiazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G748-0169

Molecular Formula

C20H19N5O3S (C20 H19 N5 O3 S)

Compound Name

5-(4-acetamidobenzamido)-2-[(4-methylphenyl)amino]-1,3-thiazole-4-carboxamide

IUPAC name

5-(4-acetamidobenzamido)-2-[(4-methylphenyl)amino]-13-thiazole-4-carboxamide

SMILES

CC(Nc(cc1)ccc1C(Nc1c(C(N)=O)nc(Nc2ccc(C)cc2)s1)=O)=O

InChI

InChI=1S/C20H19N5O3S/c1-11-3-7-15(8-4-11)23-20-24-16(17(21)27)19(29-20)25-18(28)13-5-9-14(10-6-13)22-12(2)26/h3-10H,1-2H3,(H2,21,27)(H,22,26)(H,23,24)(H,25,28)

InChI Key

RWNDPFJQAMDBNT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09779834

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

409.47

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

5.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.712

Distribution Coefficient, logD

2.656

Water Solubility, LogSw

-3.36

Polar Surface Area

99.156

Acid Dissociation Constant (pKa)

8.26

Base Dissociation Constant (pKb)

-0.73

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

G748-0169 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G748-0169 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G748-0169?
Check Price and Availability of G748-0169, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G748-0169 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G748-0169
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G748-0169
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G748-0169 available by request