G749-0300 Screening compound: 2-{[1-(2,3-dimethylphenyl)-5,7-dimethyl-4-oxo-1H,4H-pyrido[2,3-d]pyrimidin-2-yl]sulfanyl}-N-(2-methoxyphenyl)acetamide

G749-0300 Screening compound: 2-{[1-(2,3-dimethylphenyl)-5,7-dimethyl-4-oxo-1H,4H-pyrido[2,3-d]pyrimidin-2-yl]sulfanyl}-N-(2-methoxyphenyl)acetamide
G749-0300 Screening compound: 2-{[1-(2,3-dimethylphenyl)-5,7-dimethyl-4-oxo-1H,4H-pyrido[2,3-d]pyrimidin-2-yl]sulfanyl}-N-(2-methoxyphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G749-0300
2-{[1-(2,3-dimethylphenyl)-5,7-dimethyl-4-oxo-1H,4H-pyrido[2,3-d]pyrimidin-2-yl]sulfanyl}-N-(2-methoxyphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G749-0300

Molecular Formula

C26H26N4O3S (C26 H26 N4 O3 S)

Compound Name

2-{[1-(2,3-dimethylphenyl)-5,7-dimethyl-4-oxo-1H,4H-pyrido[2,3-d]pyrimidin-2-yl]sulfanyl}-N-(2-methoxyphenyl)acetamide

IUPAC name

2-{[1-(23-dimethylphenyl)-57-dimethyl-4-oxo-1H4H-pyrido[23-d]pyrimidin-2-yl]sulfanyl}-N-(2-methoxyphenyl)acetamide

SMILES

Cc1cccc(N(c2c3c(C)cc(C)n2)C(SCC(Nc(cccc2)c2OC)=O)=NC3=O)c1C

InChI

InChI=1S/C26H26N4O3S/c1-15-9-8-11-20(18(15)4)30-24-23(16(2)13-17(3)27-24)25(32)29-26(30)34-14-22(31)28-19-10-6-7-12-21(19)33-5/h6-13H,14H2,1-5H3,(H,28,31)

InChI Key

DETQGDWVGISJJP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15031270

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

474.58

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.931

Distribution Coefficient, logD

4.715

Water Solubility, LogSw

-4.69

Polar Surface Area

64.383

Acid Dissociation Constant (pKa)

11.67

Base Dissociation Constant (pKb)

7.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.10

G749-0300 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with G749-0300 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G749-0300?
Check Price and Availability of G749-0300, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G749-0300 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G749-0300
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G749-0300
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G749-0300 available by request