G749-0356 Screening compound: N-(5-chloro-2-methoxyphenyl)-2-{[4-oxo-1-(prop-2-en-1-yl)-1H,4H-pyrido[2,3-d]pyrimidin-2-yl]sulfanyl}acetamide

G749-0356 Screening compound: N-(5-chloro-2-methoxyphenyl)-2-{[4-oxo-1-(prop-2-en-1-yl)-1H,4H-pyrido[2,3-d]pyrimidin-2-yl]sulfanyl}acetamide
G749-0356 Screening compound: N-(5-chloro-2-methoxyphenyl)-2-{[4-oxo-1-(prop-2-en-1-yl)-1H,4H-pyrido[2,3-d]pyrimidin-2-yl]sulfanyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G749-0356
N-(5-chloro-2-methoxyphenyl)-2-{[4-oxo-1-(prop-2-en-1-yl)-1H,4H-pyrido[2,3-d]pyrimidin-2-yl]sulfanyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G749-0356

Molecular Formula

C19H17ClN4O3S (C19 H17 ClN4 O3 S)

Compound Name

N-(5-chloro-2-methoxyphenyl)-2-{[4-oxo-1-(prop-2-en-1-yl)-1H,4H-pyrido[2,3-d]pyrimidin-2-yl]sulfanyl}acetamide

IUPAC name

N-(5-chloro-2-methoxyphenyl)-2-{[4-oxo-1-(prop-2-en-1-yl)-1H4H-pyrido[23-d]pyrimidin-2-yl]sulfanyl}acetamide

SMILES

COc(ccc(Cl)c1)c1NC(CSC(N(CC=C)c1c2cccn1)=NC2=O)=O

InChI

InChI=1S/C19H17ClN4O3S/c1-3-9-24-17-13(5-4-8-21-17)18(26)23-19(24)28-11-16(25)22-14-10-12(20)6-7-15(14)27-2/h3-8,10H,1,9,11H2,2H3,(H,22,25)

InChI Key

GKLRQCAMKRDNQC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27155699

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

416.89

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.842

Distribution Coefficient, logD

2.839

Water Solubility, LogSw

-3.56

Polar Surface Area

66.171

Acid Dissociation Constant (pKa)

9.70

Base Dissociation Constant (pKb)

1.72

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.80

G749-0356 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G749-0356 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G749-0356?
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What is the minimum amount of G749-0356 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G749-0356
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G749-0356
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G749-0356 available by request