G754-0141 Screening compound: 8-{[2-oxo-2-(1,2,3,4-tetrahydroquinolin-1-yl)ethyl]sulfanyl}-9-phenyl-6,9-dihydro-1H-purin-6-one

G754-0141 Screening compound: 8-{[2-oxo-2-(1,2,3,4-tetrahydroquinolin-1-yl)ethyl]sulfanyl}-9-phenyl-6,9-dihydro-1H-purin-6-one
G754-0141 Screening compound: 8-{[2-oxo-2-(1,2,3,4-tetrahydroquinolin-1-yl)ethyl]sulfanyl}-9-phenyl-6,9-dihydro-1H-purin-6-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G754-0141
8-{[2-oxo-2-(1,2,3,4-tetrahydroquinolin-1-yl)ethyl]sulfanyl}-9-phenyl-6,9-dihydro-1H-purin-6-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G754-0141

Molecular Formula

C22H19N5O2S (C22 H19 N5 O2 S)

Compound Name

8-{[2-oxo-2-(1,2,3,4-tetrahydroquinolin-1-yl)ethyl]sulfanyl}-9-phenyl-6,9-dihydro-1H-purin-6-one

IUPAC name

8-{[2-oxo-2-(1234-tetrahydroquinolin-1-yl)ethyl]sulfanyl}-9-phenyl-69-dihydro-1H-purin-6-one

SMILES

O=C(CSc(n1-c2ccccc2)nc2c1N=CNC2=O)N(CCC1)c2c1cccc2

InChI

InChI=1S/C22H19N5O2S/c28-18(26-12-6-8-15-7-4-5-11-17(15)26)13-30-22-25-19-20(23-14-24-21(19)29)27(22)16-9-2-1-3-10-16/h1-5,7,9-11,14H,6,8,12-13H2,(H,23,24,29)

InChI Key

GLEOPLOSSPOPIQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27155726

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

417.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.839

Distribution Coefficient, logD

2.837

Water Solubility, LogSw

-3.44

Polar Surface Area

63.231

Acid Dissociation Constant (pKa)

9.95

Base Dissociation Constant (pKb)

1.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

G754-0141 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiviral Library (67538 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G754-0141 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G754-0141?
Check Price and Availability of G754-0141, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G754-0141 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G754-0141
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G754-0141
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G754-0141 available by request