G756-0366 Screening compound: N-[4-methyl-3-({4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methoxy)phenyl]-2-phenoxypropanamide

G756-0366 Screening compound: N-[4-methyl-3-({4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methoxy)phenyl]-2-phenoxypropanamide
G756-0366 Screening compound: N-[4-methyl-3-({4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methoxy)phenyl]-2-phenoxypropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G756-0366
N-[4-methyl-3-({4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methoxy)phenyl]-2-phenoxypropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G756-0366

Molecular Formula

C25H23N3O4 (C25 H23 N3 O4)

Compound Name

N-[4-methyl-3-({4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methoxy)phenyl]-2-phenoxypropanamide

IUPAC name

N-[4-methyl-3-({4-oxo-4H-pyrido[12-a]pyrimidin-2-yl}methoxy)phenyl]-2-phenoxypropanamide

SMILES

CC(C(Nc1cc(OCC(N=C2N3C=CC=C2)=CC3=O)c(C)cc1)=O)Oc1ccccc1

InChI

InChI=1S/C25H23N3O4/c1-17-11-12-19(27-25(30)18(2)32-21-8-4-3-5-9-21)14-22(17)31-16-20-15-24(29)28-13-7-6-10-23(28)26-20/h3-15,18H,16H2,1-2H3,(H,27,30)/t18-/m0/s1

InChI Key

PWPNVGDFIFARDQ-SFHVURJKSA-N

MDL Number (MFCD)

MFCD27156044

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

429.48

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.469

Distribution Coefficient, logD

3.469

Water Solubility, LogSw

-3.75

Polar Surface Area

63.419

Acid Dissociation Constant (pKa)

11.57

Base Dissociation Constant (pKb)

2.61

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

16.00

G756-0366 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G756-0366 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G756-0366?
Check Price and Availability of G756-0366, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G756-0366 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G756-0366
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G756-0366
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G756-0366 available by request