G756-2274 Screening compound: N-[3-({7-chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methoxy)phenyl]-2-methoxybenzamide

G756-2274 Screening compound: N-[3-({7-chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methoxy)phenyl]-2-methoxybenzamide
G756-2274 Screening compound: N-[3-({7-chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methoxy)phenyl]-2-methoxybenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G756-2274
N-[3-({7-chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methoxy)phenyl]-2-methoxybenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G756-2274

Molecular Formula

C23H18ClN3O4 (C23 H18 ClN3 O4)

Compound Name

N-[3-({7-chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methoxy)phenyl]-2-methoxybenzamide

IUPAC name

N-[3-({7-chloro-4-oxo-4H-pyrido[12-a]pyrimidin-2-yl}methoxy)phenyl]-2-methoxybenzamide

SMILES

COc(cccc1)c1C(Nc1cccc(OCC(N=C(C=C2)N3C=C2Cl)=CC3=O)c1)=O

InChI

InChI=1S/C23H18ClN3O4/c1-30-20-8-3-2-7-19(20)23(29)26-16-5-4-6-18(11-16)31-14-17-12-22(28)27-13-15(24)9-10-21(27)25-17/h2-13H,14H2,1H3,(H,26,29)

InChI Key

HXSKDDXHOGCAAJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27156145

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

435.87

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.891

Distribution Coefficient, logD

2.885

Water Solubility, LogSw

-3.73

Polar Surface Area

64.693

Acid Dissociation Constant (pKa)

9.21

Base Dissociation Constant (pKb)

1.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.70

G756-2274 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G756-2274 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G756-2274?
Check Price and Availability of G756-2274, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G756-2274 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G756-2274
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G756-2274
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G756-2274 available by request