G760-0112 Screening compound: 1-(2-chloro-4-methylphenyl)-3-{[3-methyl-1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazol-4-yl]methyl}urea

G760-0112 Screening compound: 1-(2-chloro-4-methylphenyl)-3-{[3-methyl-1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazol-4-yl]methyl}urea
G760-0112 Screening compound: 1-(2-chloro-4-methylphenyl)-3-{[3-methyl-1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazol-4-yl]methyl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound G760-0112
1-(2-chloro-4-methylphenyl)-3-{[3-methyl-1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazol-4-yl]methyl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G760-0112

Molecular Formula

C23H22ClN5O (C23 H22 ClN5 O)

Compound Name

1-(2-chloro-4-methylphenyl)-3-{[3-methyl-1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazol-4-yl]methyl}urea

IUPAC name

1-(2-chloro-4-methylphenyl)-3-{[3-methyl-1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazol-4-yl]methyl}urea

SMILES

Cc(c(CNC(Nc(ccc(C)c1)c1Cl)=O)c1-n2cccc2)nn1-c1ccccc1

InChI

InChI=1S/C23H22ClN5O/c1-16-10-11-21(20(24)14-16)26-23(30)25-15-19-17(2)27-29(18-8-4-3-5-9-18)22(19)28-12-6-7-13-28/h3-14H,15H2,1-2H3,(H2,25,26,30)

InChI Key

CGRGTTUJOSKKEJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15033426

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

419.91

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.040

Distribution Coefficient, logD

5.040

Water Solubility, LogSw

-5.23

Polar Surface Area

50.375

Acid Dissociation Constant (pKa)

11.91

Base Dissociation Constant (pKb)

0.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

G760-0112 in Drug Discovery

Included in Screening Libraries

SH2 Library (10483 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Endocrine
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G760-0112 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G760-0112?
Check Price and Availability of G760-0112, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G760-0112 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G760-0112
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G760-0112
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G760-0112 available by request