G764-0894 Screening compound: N-(4-bromophenyl)-7'-methoxy-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]-1-carboxamide

G764-0894 Screening compound: N-(4-bromophenyl)-7'-methoxy-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]-1-carboxamide
G764-0894 Screening compound: N-(4-bromophenyl)-7'-methoxy-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G764-0894
N-(4-bromophenyl)-7'-methoxy-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G764-0894

Molecular Formula

C23H23BrN4O2 (C23 H23 BrN4 O2)

Compound Name

N-(4-bromophenyl)-7'-methoxy-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]-1-carboxamide

IUPAC name

N-(4-bromophenyl)-7'-methoxy-5'H-spiro[piperidine-44'-pyrrolo[12-a]quinoxaline]-1-carboxamide

SMILES

COc(cc1)cc(NC2(CC3)CCN3C(Nc(cc3)ccc3Br)=O)c1-n1c2ccc1

InChI

InChI=1S/C23H23BrN4O2/c1-30-18-8-9-20-19(15-18)26-23(21-3-2-12-28(20)21)10-13-27(14-11-23)22(29)25-17-6-4-16(24)5-7-17/h2-9,12,15,26H,10-11,13-14H2,1H3,(H,25,29)

InChI Key

GGKVJLAZMQLAAX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27156346

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

467.37

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.191

Distribution Coefficient, logD

5.191

Water Solubility, LogSw

-5.09

Polar Surface Area

46.759

Acid Dissociation Constant (pKa)

12.23

Base Dissociation Constant (pKb)

3.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

G764-0894 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Targeted Diversity Library (40567 compounds)

Therapeutical Diversity Annotated Library (7563 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
Targets:
  • Kinases
  • Ion Channels
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with G764-0894 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G764-0894?
Check Price and Availability of G764-0894, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G764-0894 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G764-0894
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G764-0894
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G764-0894 available by request