G764-0918 Screening compound: N-(2-fluorophenyl)-7'-methoxy-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]-1-carboxamide

G764-0918 Screening compound: N-(2-fluorophenyl)-7'-methoxy-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]-1-carboxamide
G764-0918 Screening compound: N-(2-fluorophenyl)-7'-methoxy-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G764-0918
N-(2-fluorophenyl)-7'-methoxy-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G764-0918

Molecular Formula

C23H23FN4O2 (C23 H23 FN4 O2)

Compound Name

N-(2-fluorophenyl)-7'-methoxy-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]-1-carboxamide

IUPAC name

N-(2-fluorophenyl)-7'-methoxy-5'H-spiro[piperidine-44'-pyrrolo[12-a]quinoxaline]-1-carboxamide

SMILES

COc(cc1)cc(NC2(CC3)CCN3C(Nc(cccc3)c3F)=O)c1-n1c2ccc1

InChI

InChI=1S/C23H23FN4O2/c1-30-16-8-9-20-19(15-16)26-23(21-7-4-12-28(20)21)10-13-27(14-11-23)22(29)25-18-6-3-2-5-17(18)24/h2-9,12,15,26H,10-11,13-14H2,1H3,(H,25,29)

InChI Key

DKGPVVDCLLCUAY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27156364

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

406.46

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.534

Distribution Coefficient, logD

4.534

Water Solubility, LogSw

-4.19

Polar Surface Area

46.061

Acid Dissociation Constant (pKa)

12.14

Base Dissociation Constant (pKb)

3.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

G764-0918 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds
Therapeutical areas:
  • Nervous system
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with G764-0918 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G764-0918?
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What is the minimum amount of G764-0918 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G764-0918
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G764-0918
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G764-0918 available by request