G768-0315 Screening compound: 2-(2-chlorophenyl)-7-({4-[2-(4-methoxyphenoxy)acetyl]piperazin-1-yl}methyl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one

G768-0315 Screening compound: 2-(2-chlorophenyl)-7-({4-[2-(4-methoxyphenoxy)acetyl]piperazin-1-yl}methyl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one
G768-0315 Screening compound: 2-(2-chlorophenyl)-7-({4-[2-(4-methoxyphenoxy)acetyl]piperazin-1-yl}methyl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G768-0315
2-(2-chlorophenyl)-7-({4-[2-(4-methoxyphenoxy)acetyl]piperazin-1-yl}methyl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G768-0315

Molecular Formula

C25H24ClN5O4S (C25 H24 ClN5 O4 S)

Compound Name

2-(2-chlorophenyl)-7-({4-[2-(4-methoxyphenoxy)acetyl]piperazin-1-yl}methyl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one

IUPAC name

2-(2-chlorophenyl)-7-({4-[2-(4-methoxyphenoxy)acetyl]piperazin-1-yl}methyl)-5H-[134]thiadiazolo[32-a]pyrimidin-5-one

SMILES

COc(cc1)ccc1OCC(N1CCN(CC(N=C2SC(c(cccc3)c3Cl)=NN22)=CC2=O)CC1)=O

InChI

InChI=1S/C25H24ClN5O4S/c1-34-18-6-8-19(9-7-18)35-16-23(33)30-12-10-29(11-13-30)15-17-14-22(32)31-25(27-17)36-24(28-31)20-4-2-3-5-21(20)26/h2-9,14H,10-13,15-16H2,1H3

InChI Key

OOMKIAMGQFQPGU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27156562

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

526.02

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.487

Distribution Coefficient, logD

2.481

Water Solubility, LogSw

-3.30

Polar Surface Area

72.975

Acid Dissociation Constant (pKa)

25.23

Base Dissociation Constant (pKb)

5.58

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

G768-0315 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G768-0315 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G768-0315?
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What is the minimum amount of G768-0315 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G768-0315
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G768-0315
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G768-0315 available by request