G771-0226 Screening compound: 4-methoxy-N-[1-phenyl-3-(thiophen-2-yl)-1H-pyrazol-5-yl]benzamide

G771-0226 Screening compound: 4-methoxy-N-[1-phenyl-3-(thiophen-2-yl)-1H-pyrazol-5-yl]benzamide
G771-0226 Screening compound: 4-methoxy-N-[1-phenyl-3-(thiophen-2-yl)-1H-pyrazol-5-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G771-0226
4-methoxy-N-[1-phenyl-3-(thiophen-2-yl)-1H-pyrazol-5-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G771-0226

Molecular Formula

C21H17N3O2S (C21 H17 N3 O2 S)

Compound Name

4-methoxy-N-[1-phenyl-3-(thiophen-2-yl)-1H-pyrazol-5-yl]benzamide

IUPAC name

4-methoxy-N-[1-phenyl-3-(thiophen-2-yl)-1H-pyrazol-5-yl]benzamide

SMILES

COc(cc1)ccc1C(Nc1cc(-c2cccs2)nn1-c1ccccc1)=O

InChI

InChI=1S/C21H17N3O2S/c1-26-17-11-9-15(10-12-17)21(25)22-20-14-18(19-8-5-13-27-19)23-24(20)16-6-3-2-4-7-16/h2-14H,1H3,(H,22,25)

InChI Key

UHDIMMGPQNQMHH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15035012

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

375.45

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.868

Distribution Coefficient, logD

4.868

Water Solubility, LogSw

-4.64

Polar Surface Area

46.055

Acid Dissociation Constant (pKa)

12.10

Base Dissociation Constant (pKb)

-3.24

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.80

G771-0226 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G771-0226 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G771-0226?
Check Price and Availability of G771-0226, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G771-0226 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G771-0226
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G771-0226
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G771-0226 available by request