G774-0225 Screening compound: 2-{1-[4-(2,5-dimethyl-1H-pyrrol-1-yl)-3-methyl-1-phenyl-1H-pyrazol-5-yl]piperidine-4-carbonyl}-1,2,3,4-tetrahydroisoquinoline

G774-0225 Screening compound: 2-{1-[4-(2,5-dimethyl-1H-pyrrol-1-yl)-3-methyl-1-phenyl-1H-pyrazol-5-yl]piperidine-4-carbonyl}-1,2,3,4-tetrahydroisoquinoline
G774-0225 Screening compound: 2-{1-[4-(2,5-dimethyl-1H-pyrrol-1-yl)-3-methyl-1-phenyl-1H-pyrazol-5-yl]piperidine-4-carbonyl}-1,2,3,4-tetrahydroisoquinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound G774-0225
2-{1-[4-(2,5-dimethyl-1H-pyrrol-1-yl)-3-methyl-1-phenyl-1H-pyrazol-5-yl]piperidine-4-carbonyl}-1,2,3,4-tetrahydroisoquinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G774-0225

Molecular Formula

C31H35N5O (C31 H35 N5 O)

Compound Name

2-{1-[4-(2,5-dimethyl-1H-pyrrol-1-yl)-3-methyl-1-phenyl-1H-pyrazol-5-yl]piperidine-4-carbonyl}-1,2,3,4-tetrahydroisoquinoline

IUPAC name

2-{1-[4-(25-dimethyl-1H-pyrrol-1-yl)-3-methyl-1-phenyl-1H-pyrazol-5-yl]piperidine-4-carbonyl}-1234-tetrahydroisoquinoline

SMILES

Cc1ccc(C)n1-c(c(C)nn1-c2ccccc2)c1N(CC1)CCC1C(N(CC1)Cc2c1cccc2)=O

InChI

InChI=1S/C31H35N5O/c1-22-13-14-23(2)35(22)29-24(3)32-36(28-11-5-4-6-12-28)30(29)33-18-16-26(17-19-33)31(37)34-20-15-25-9-7-8-10-27(25)21-34/h4-14,26H,15-21H2,1-3H3

InChI Key

OAUSCJBFVCWMGN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15035141

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

493.65

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.087

Distribution Coefficient, logD

5.087

Water Solubility, LogSw

-4.87

Polar Surface Area

35.512

Acid Dissociation Constant (pKa)

22.38

Base Dissociation Constant (pKb)

3.27

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.50

G774-0225 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G774-0225 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G774-0225?
Check Price and Availability of G774-0225, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G774-0225 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G774-0225
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G774-0225
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G774-0225 available by request