G783-0205 Screening compound: (2E)-1-{4-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]piperazin-1-yl}-3-phenylprop-2-en-1-one

G783-0205 Screening compound: (2E)-1-{4-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]piperazin-1-yl}-3-phenylprop-2-en-1-one
G783-0205 Screening compound: (2E)-1-{4-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]piperazin-1-yl}-3-phenylprop-2-en-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G783-0205
(2E)-1-{4-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]piperazin-1-yl}-3-phenylprop-2-en-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G783-0205

Molecular Formula

C21H19ClN4O2 (C21 H19 ClN4 O2)

Compound Name

(2E)-1-{4-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]piperazin-1-yl}-3-phenylprop-2-en-1-one

IUPAC name

(2E)-1-{4-[3-(4-chlorophenyl)-124-oxadiazol-5-yl]piperazin-1-yl}-3-phenylprop-2-en-1-one

SMILES

O=C(/C=C/c1ccccc1)N(CC1)CCN1c1nc(-c(cc2)ccc2Cl)no1

InChI

InChI=1S/C21H19ClN4O2/c22-18-9-7-17(8-10-18)20-23-21(28-24-20)26-14-12-25(13-15-26)19(27)11-6-16-4-2-1-3-5-16/h1-11H,12-15H2

InChI Key

COBBINHCZXYLIC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15035785

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

394.86

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.577

Distribution Coefficient, logD

4.577

Water Solubility, LogSw

-5.05

Polar Surface Area

51.368

Acid Dissociation Constant (pKa)

23.82

Base Dissociation Constant (pKb)

1.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

G783-0205 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Covalent Inhibitors Library (7986 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
Structure:
  • Cyclic compounds
  • 3D
  • Fragments

References: we are preparing a list of scientific research reports with G783-0205 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G783-0205?
Check Price and Availability of G783-0205, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G783-0205 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G783-0205
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G783-0205
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G783-0205 available by request