G786-0262 Screening compound: N-(4-butylphenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine

G786-0262 Screening compound: N-(4-butylphenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine
G786-0262 Screening compound: N-(4-butylphenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound G786-0262
N-(4-butylphenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G786-0262

Molecular Formula

C20H25N5 (C20 H25 N5)

Compound Name

N-(4-butylphenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine

IUPAC name

N-(4-butylphenyl)-2-(35-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine

SMILES

CCCCc(cc1)ccc1Nc1cc(C)nc(-n2nc(C)cc2C)n1

InChI

InChI=1S/C20H25N5/c1-5-6-7-17-8-10-18(11-9-17)22-19-13-14(2)21-20(23-19)25-16(4)12-15(3)24-25/h8-13H,5-7H2,1-4H3,(H,21,22,23)

InChI Key

KDGHVMIYHIGTQT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09247925

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

335.45

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.126

Distribution Coefficient, logD

4.586

Water Solubility, LogSw

-5.07

Polar Surface Area

40.894

Acid Dissociation Constant (pKa)

19.54

Base Dissociation Constant (pKb)

7.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.00

G786-0262 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with G786-0262 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G786-0262?
Check Price and Availability of G786-0262, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G786-0262 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G786-0262
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G786-0262
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G786-0262 available by request