G786-1045 Screening compound: ethyl 2-(4-ethoxybenzamido)-1,3-thiazole-4-carboxylate

G786-1045 Screening compound: ethyl 2-(4-ethoxybenzamido)-1,3-thiazole-4-carboxylate
G786-1045 Screening compound: ethyl 2-(4-ethoxybenzamido)-1,3-thiazole-4-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound G786-1045
ethyl 2-(4-ethoxybenzamido)-1,3-thiazole-4-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G786-1045

Molecular Formula

C15H16N2O4S (C15 H16 N2 O4 S)

Compound Name

ethyl 2-(4-ethoxybenzamido)-1,3-thiazole-4-carboxylate

IUPAC name

ethyl 2-(4-ethoxybenzamido)-13-thiazole-4-carboxylate

SMILES

CCOC(c1csc(NC(c(cc2)ccc2OCC)=O)n1)=O

InChI

InChI=1S/C15H16N2O4S/c1-3-20-11-7-5-10(6-8-11)13(18)17-15-16-12(9-22-15)14(19)21-4-2/h5-9H,3-4H2,1-2H3,(H,16,17,18)

InChI Key

PMQMLXZQOLPKJU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02657780

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

320.37

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.277

Distribution Coefficient, logD

3.210

Water Solubility, LogSw

-3.39

Polar Surface Area

61.253

Acid Dissociation Constant (pKa)

8.18

Base Dissociation Constant (pKb)

-3.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.70

G786-1045 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anti-Aging Library (44940 compounds)

Anti-infective Library (19449 compounds)

Anticancer Library (62698 compounds)

Protein-Protein Interaction Library (218420 compounds)

SH2 Library (10483 compounds)

Selective Target Activity Profiling Library (14702 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Therapeutical Diversity Annotated Library (7563 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Infections
  • Immune system
  • animal
  • Cancer
  • Cancer
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Immune system
Targets:
  • Kinases
  • Proteases
Mechanism of action:
  • Epigenetic
  • PPI modulators
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G786-1045 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G786-1045?
Check Price and Availability of G786-1045, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G786-1045 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G786-1045
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G786-1045
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G786-1045 available by request