G786-1153 Screening compound: N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]-4-(1,2,3,4-tetrahydroquinoline-1-sulfonyl)benzamide

G786-1153 Screening compound: N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]-4-(1,2,3,4-tetrahydroquinoline-1-sulfonyl)benzamide
G786-1153 Screening compound: N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]-4-(1,2,3,4-tetrahydroquinoline-1-sulfonyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G786-1153
N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]-4-(1,2,3,4-tetrahydroquinoline-1-sulfonyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G786-1153

Molecular Formula

C24H20N4O3S2 (C24 H20 N4 O3 S2)

Compound Name

N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]-4-(1,2,3,4-tetrahydroquinoline-1-sulfonyl)benzamide

IUPAC name

N-[4-(pyridin-4-yl)-13-thiazol-2-yl]-4-(1234-tetrahydroquinoline-1-sulfonyl)benzamide

SMILES

O=C(c(cc1)ccc1S(N(CCC1)c2c1cccc2)(=O)=O)Nc1nc(-c2ccncc2)cs1

InChI

InChI=1S/C24H20N4O3S2/c29-23(27-24-26-21(16-32-24)17-11-13-25-14-12-17)19-7-9-20(10-8-19)33(30,31)28-15-3-5-18-4-1-2-6-22(18)28/h1-2,4,6-14,16H,3,5,15H2,(H,26,27,29)

InChI Key

AMTKURZBKKEINF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04416100

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

476.58

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.287

Distribution Coefficient, logD

4.285

Water Solubility, LogSw

-4.25

Polar Surface Area

73.685

Acid Dissociation Constant (pKa)

9.74

Base Dissociation Constant (pKb)

4.25

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

G786-1153 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • GPCR
  • Proteases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G786-1153 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G786-1153?
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What is the minimum amount of G786-1153 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G786-1153
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G786-1153
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G786-1153 available by request