G786-1158 Screening compound: N-[4-(5-methylfuran-2-yl)-1,3-thiazol-2-yl]-[1,1'-biphenyl]-4-carboxamide

G786-1158 Screening compound: N-[4-(5-methylfuran-2-yl)-1,3-thiazol-2-yl]-[1,1'-biphenyl]-4-carboxamide
G786-1158 Screening compound: N-[4-(5-methylfuran-2-yl)-1,3-thiazol-2-yl]-[1,1'-biphenyl]-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G786-1158
N-[4-(5-methylfuran-2-yl)-1,3-thiazol-2-yl]-[1,1'-biphenyl]-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G786-1158

Molecular Formula

C21H16N2O2S (C21 H16 N2 O2 S)

Compound Name

N-[4-(5-methylfuran-2-yl)-1,3-thiazol-2-yl]-[1,1'-biphenyl]-4-carboxamide

IUPAC name

N-[4-(5-methylfuran-2-yl)-13-thiazol-2-yl]-[11'-biphenyl]-4-carboxamide

SMILES

Cc1ccc(-c2csc(NC(c(cc3)ccc3-c3ccccc3)=O)n2)o1

InChI

InChI=1S/C21H16N2O2S/c1-14-7-12-19(25-14)18-13-26-21(22-18)23-20(24)17-10-8-16(9-11-17)15-5-3-2-4-6-15/h2-13H,1H3,(H,22,23,24)

InChI Key

UVTLQYLBIYMCDX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04416158

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

360.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.802

Distribution Coefficient, logD

5.801

Water Solubility, LogSw

-5.78

Polar Surface Area

40.925

Acid Dissociation Constant (pKa)

10.28

Base Dissociation Constant (pKb)

0.72

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.80

G786-1158 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Antiviral Annotated Library (21441 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Selective Target Activity Profiling Library (14702 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Therapeutical Diversity Annotated Library (7563 compounds)

Akt-Targeted Library (14764 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Proteases
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with G786-1158 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G786-1158?
Check Price and Availability of G786-1158, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G786-1158 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G786-1158
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G786-1158
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G786-1158 available by request