G786-1263 Screening compound: 4-{methyl[(oxolan-2-yl)methyl]sulfamoyl}-N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]benzamide

G786-1263 Screening compound: 4-{methyl[(oxolan-2-yl)methyl]sulfamoyl}-N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]benzamide
G786-1263 Screening compound: 4-{methyl[(oxolan-2-yl)methyl]sulfamoyl}-N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G786-1263
4-{methyl[(oxolan-2-yl)methyl]sulfamoyl}-N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G786-1263

Molecular Formula

C21H22N4O4S2 (C21 H22 N4 O4 S2)

Compound Name

4-{methyl[(oxolan-2-yl)methyl]sulfamoyl}-N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]benzamide

IUPAC name

4-{methyl[(oxolan-2-yl)methyl]sulfamoyl}-N-[4-(pyridin-4-yl)-13-thiazol-2-yl]benzamide

SMILES

CN(CC1OCCC1)S(c(cc1)ccc1C(Nc1nc(-c2ccncc2)cs1)=O)(=O)=O

InChI

InChI=1S/C21H22N4O4S2/c1-25(13-17-3-2-12-29-17)31(27,28)18-6-4-16(5-7-18)20(26)24-21-23-19(14-30-21)15-8-10-22-11-9-15/h4-11,14,17H,2-3,12-13H2,1H3,(H,23,24,26)/t17-/m1/s1

InChI Key

NJYDOSVNKPTVLF-QGZVFWFLSA-N

MDL Number (MFCD)

MFCD05923612

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

458.56

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.811

Distribution Coefficient, logD

2.809

Water Solubility, LogSw

-3.51

Polar Surface Area

83.751

Acid Dissociation Constant (pKa)

9.74

Base Dissociation Constant (pKb)

4.25

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

28.60

G786-1263 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Allosteric Kinases Inhibitors Library (23117 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Proteases

References: we are preparing a list of scientific research reports with G786-1263 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G786-1263?
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What is the minimum amount of G786-1263 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G786-1263
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G786-1263
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G786-1263 available by request