G786-1281 Screening compound: N-(4-methyl-1,3-thiazol-2-yl)-2-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}acetamide

G786-1281 Screening compound: N-(4-methyl-1,3-thiazol-2-yl)-2-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}acetamide
G786-1281 Screening compound: N-(4-methyl-1,3-thiazol-2-yl)-2-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G786-1281
N-(4-methyl-1,3-thiazol-2-yl)-2-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G786-1281

Molecular Formula

C15H12N6OS3 (C15 H12 N6 OS3)

Compound Name

N-(4-methyl-1,3-thiazol-2-yl)-2-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}acetamide

IUPAC name

N-(4-methyl-13-thiazol-2-yl)-2-{[6-(thiophen-2-yl)-[124]triazolo[43-b]pyridazin-3-yl]sulfanyl}acetamide

SMILES

Cc1csc(NC(CSc2nnc(cc3)n2nc3-c2cccs2)=O)n1

InChI

InChI=1S/C15H12N6OS3/c1-9-7-24-14(16-9)17-13(22)8-25-15-19-18-12-5-4-10(20-21(12)15)11-3-2-6-23-11/h2-7H,8H2,1H3,(H,16,17,22)

InChI Key

IQHFMMLEZZSTRZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06711380

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.5

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.827

Distribution Coefficient, logD

2.821

Water Solubility, LogSw

-3.15

Polar Surface Area

66.728

Acid Dissociation Constant (pKa)

9.25

Base Dissociation Constant (pKb)

0.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.30

G786-1281 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with G786-1281 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G786-1281?
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What is the minimum amount of G786-1281 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G786-1281
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G786-1281
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G786-1281 available by request