G786-1650 Screening compound: N-[6-(tert-butylsulfamoyl)-1,3-benzothiazol-2-yl]-4-(2,5-dioxopyrrolidin-1-yl)benzamide

G786-1650 Screening compound: N-[6-(tert-butylsulfamoyl)-1,3-benzothiazol-2-yl]-4-(2,5-dioxopyrrolidin-1-yl)benzamide
G786-1650 Screening compound: N-[6-(tert-butylsulfamoyl)-1,3-benzothiazol-2-yl]-4-(2,5-dioxopyrrolidin-1-yl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G786-1650
N-[6-(tert-butylsulfamoyl)-1,3-benzothiazol-2-yl]-4-(2,5-dioxopyrrolidin-1-yl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G786-1650

Molecular Formula

C22H22N4O5S2 (C22 H22 N4 O5 S2)

Compound Name

N-[6-(tert-butylsulfamoyl)-1,3-benzothiazol-2-yl]-4-(2,5-dioxopyrrolidin-1-yl)benzamide

IUPAC name

N-[6-(tert-butylsulfamoyl)-13-benzothiazol-2-yl]-4-(25-dioxopyrrolidin-1-yl)benzamide

SMILES

CC(C)(C)NS(c(cc1)cc2c1nc(NC(c(cc1)ccc1N(C(CC1)=O)C1=O)=O)s2)(=O)=O

InChI

InChI=1S/C22H22N4O5S2/c1-22(2,3)25-33(30,31)15-8-9-16-17(12-15)32-21(23-16)24-20(29)13-4-6-14(7-5-13)26-18(27)10-11-19(26)28/h4-9,12,25H,10-11H2,1-3H3,(H,23,24,29)

InChI Key

MXDFVCANPDCWIV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06008344

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

486.57

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.916

Distribution Coefficient, logD

1.908

Water Solubility, LogSw

-2.82

Polar Surface Area

103.627

Acid Dissociation Constant (pKa)

9.11

Base Dissociation Constant (pKb)

-1.80

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

G786-1650 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Kinases
  • Proteases
  • Phosphatases

References: we are preparing a list of scientific research reports with G786-1650 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G786-1650?
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What is the minimum amount of G786-1650 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G786-1650
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G786-1650
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G786-1650 available by request