G786-1654 Screening compound: 3-(dimethylamino)-N-{6-[(2-methylpropyl)sulfamoyl]-1,3-benzothiazol-2-yl}benzamide

G786-1654 Screening compound: 3-(dimethylamino)-N-{6-[(2-methylpropyl)sulfamoyl]-1,3-benzothiazol-2-yl}benzamide
G786-1654 Screening compound: 3-(dimethylamino)-N-{6-[(2-methylpropyl)sulfamoyl]-1,3-benzothiazol-2-yl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G786-1654
3-(dimethylamino)-N-{6-[(2-methylpropyl)sulfamoyl]-1,3-benzothiazol-2-yl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G786-1654

Molecular Formula

C20H24N4O3S2 (C20 H24 N4 O3 S2)

Compound Name

3-(dimethylamino)-N-{6-[(2-methylpropyl)sulfamoyl]-1,3-benzothiazol-2-yl}benzamide

IUPAC name

3-(dimethylamino)-N-{6-[(2-methylpropyl)sulfamoyl]-13-benzothiazol-2-yl}benzamide

SMILES

CC(C)CNS(c(cc1)cc2c1nc(NC(c1cc(N(C)C)ccc1)=O)s2)(=O)=O

InChI

InChI=1S/C20H24N4O3S2/c1-13(2)12-21-29(26,27)16-8-9-17-18(11-16)28-20(22-17)23-19(25)14-6-5-7-15(10-14)24(3)4/h5-11,13,21H,12H2,1-4H3,(H,22,23,25)

InChI Key

FOSWLYQSFTWGLY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05744678

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.57

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.619

Distribution Coefficient, logD

4.619

Water Solubility, LogSw

-4.32

Polar Surface Area

77.926

Acid Dissociation Constant (pKa)

10.84

Base Dissociation Constant (pKb)

7.25

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.00

G786-1654 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G786-1654 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G786-1654?
Check Price and Availability of G786-1654, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G786-1654 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G786-1654
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G786-1654
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G786-1654 available by request