G786-2082 Screening compound: 4-(benzenesulfonyl)-8-(2-chloro-6-fluorobenzoyl)-1-oxa-4,8-diazaspiro[4.5]decane

G786-2082 Screening compound: 4-(benzenesulfonyl)-8-(2-chloro-6-fluorobenzoyl)-1-oxa-4,8-diazaspiro[4.5]decane
G786-2082 Screening compound: 4-(benzenesulfonyl)-8-(2-chloro-6-fluorobenzoyl)-1-oxa-4,8-diazaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound G786-2082
4-(benzenesulfonyl)-8-(2-chloro-6-fluorobenzoyl)-1-oxa-4,8-diazaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G786-2082

Molecular Formula

C20H20ClFN2O4S (C20 H20 ClFN2 O4 S)

Compound Name

4-(benzenesulfonyl)-8-(2-chloro-6-fluorobenzoyl)-1-oxa-4,8-diazaspiro[4.5]decane

IUPAC name

4-(benzenesulfonyl)-8-(2-chloro-6-fluorobenzoyl)-1-oxa-48-diazaspiro[4.5]decane

SMILES

O=C(c(c(F)ccc1)c1Cl)N(CC1)CCC11OCCN1S(c1ccccc1)(=O)=O

InChI

InChI=1S/C20H20ClFN2O4S/c21-16-7-4-8-17(22)18(16)19(25)23-11-9-20(10-12-23)24(13-14-28-20)29(26,27)15-5-2-1-3-6-15/h1-8H,9-14H2

InChI Key

UVPDCLKGEPMMTM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07195866

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

438.91

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.501

Distribution Coefficient, logD

2.501

Water Solubility, LogSw

-3.24

Polar Surface Area

55.576

Acid Dissociation Constant (pKa)

27.30

Base Dissociation Constant (pKb)

-3.42

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.00

G786-2082 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with G786-2082 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G786-2082?
Check Price and Availability of G786-2082, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G786-2082 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G786-2082
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G786-2082
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G786-2082 available by request