G786-2119 Screening compound: 2-({2-phenylimidazo[1,2-b]pyridazin-6-yl}sulfanyl)-1-(1,2,3,4-tetrahydroquinolin-1-yl)ethan-1-one

G786-2119 Screening compound: 2-({2-phenylimidazo[1,2-b]pyridazin-6-yl}sulfanyl)-1-(1,2,3,4-tetrahydroquinolin-1-yl)ethan-1-one
G786-2119 Screening compound: 2-({2-phenylimidazo[1,2-b]pyridazin-6-yl}sulfanyl)-1-(1,2,3,4-tetrahydroquinolin-1-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G786-2119
2-({2-phenylimidazo[1,2-b]pyridazin-6-yl}sulfanyl)-1-(1,2,3,4-tetrahydroquinolin-1-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G786-2119

Molecular Formula

C23H20N4OS (C23 H20 N4 OS)

Compound Name

2-({2-phenylimidazo[1,2-b]pyridazin-6-yl}sulfanyl)-1-(1,2,3,4-tetrahydroquinolin-1-yl)ethan-1-one

IUPAC name

2-({2-phenylimidazo[12-b]pyridazin-6-yl}sulfanyl)-1-(1234-tetrahydroquinolin-1-yl)ethan-1-one

SMILES

O=C(CSc(cc1)nn2c1nc(-c1ccccc1)c2)N(CCC1)c2c1cccc2

InChI

InChI=1S/C23H20N4OS/c28-23(26-14-6-10-18-9-4-5-11-20(18)26)16-29-22-13-12-21-24-19(15-27(21)25-22)17-7-2-1-3-8-17/h1-5,7-9,11-13,15H,6,10,14,16H2

InChI Key

HCQCIEMKUWJYHF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06733205

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

400.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.646

Distribution Coefficient, logD

4.646

Water Solubility, LogSw

-4.45

Polar Surface Area

33.809

Acid Dissociation Constant (pKa)

19.56

Base Dissociation Constant (pKb)

4.66

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

G786-2119 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
  • Cardiovascular
Mechanism of action:
  • PPI modulators
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with G786-2119 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G786-2119?
Check Price and Availability of G786-2119, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G786-2119 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G786-2119
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G786-2119
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G786-2119 available by request