G786-2137 Screening compound: N-(3,5-dimethylphenyl)-2-{[2-(4-methoxyphenyl)imidazo[1,2-b]pyridazin-6-yl]sulfanyl}acetamide

G786-2137 Screening compound: N-(3,5-dimethylphenyl)-2-{[2-(4-methoxyphenyl)imidazo[1,2-b]pyridazin-6-yl]sulfanyl}acetamide
G786-2137 Screening compound: N-(3,5-dimethylphenyl)-2-{[2-(4-methoxyphenyl)imidazo[1,2-b]pyridazin-6-yl]sulfanyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G786-2137
N-(3,5-dimethylphenyl)-2-{[2-(4-methoxyphenyl)imidazo[1,2-b]pyridazin-6-yl]sulfanyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G786-2137

Molecular Formula

C23H22N4O2S (C23 H22 N4 O2 S)

Compound Name

N-(3,5-dimethylphenyl)-2-{[2-(4-methoxyphenyl)imidazo[1,2-b]pyridazin-6-yl]sulfanyl}acetamide

IUPAC name

N-(35-dimethylphenyl)-2-{[2-(4-methoxyphenyl)imidazo[12-b]pyridazin-6-yl]sulfanyl}acetamide

SMILES

Cc1cc(NC(CSc(cc2)nn3c2nc(-c(cc2)ccc2OC)c3)=O)cc(C)c1

InChI

InChI=1S/C23H22N4O2S/c1-15-10-16(2)12-18(11-15)24-22(28)14-30-23-9-8-21-25-20(13-27(21)26-23)17-4-6-19(29-3)7-5-17/h4-13H,14H2,1-3H3,(H,24,28)

InChI Key

MPNHPTCEVVIDQN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06733250

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

418.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.993

Distribution Coefficient, logD

4.992

Water Solubility, LogSw

-4.54

Polar Surface Area

49.445

Acid Dissociation Constant (pKa)

13.08

Base Dissociation Constant (pKb)

4.45

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

G786-2137 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G786-2137 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G786-2137?
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What is the minimum amount of G786-2137 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G786-2137
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G786-2137
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G786-2137 available by request