G786-2203 Screening compound: 2-(4-methoxyphenyl)-6-{[(2-methylphenyl)methyl]sulfanyl}imidazo[1,2-b]pyridazine

G786-2203 Screening compound: 2-(4-methoxyphenyl)-6-{[(2-methylphenyl)methyl]sulfanyl}imidazo[1,2-b]pyridazine
G786-2203 Screening compound: 2-(4-methoxyphenyl)-6-{[(2-methylphenyl)methyl]sulfanyl}imidazo[1,2-b]pyridazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G786-2203
2-(4-methoxyphenyl)-6-{[(2-methylphenyl)methyl]sulfanyl}imidazo[1,2-b]pyridazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G786-2203

Molecular Formula

C21H19N3OS (C21 H19 N3 OS)

Compound Name

2-(4-methoxyphenyl)-6-{[(2-methylphenyl)methyl]sulfanyl}imidazo[1,2-b]pyridazine

IUPAC name

2-(4-methoxyphenyl)-6-{[(2-methylphenyl)methyl]sulfanyl}imidazo[12-b]pyridazine

SMILES

Cc1c(CSc(cc2)nn3c2nc(-c(cc2)ccc2OC)c3)cccc1

InChI

InChI=1S/C21H19N3OS/c1-15-5-3-4-6-17(15)14-26-21-12-11-20-22-19(13-24(20)23-21)16-7-9-18(25-2)10-8-16/h3-13H,14H2,1-2H3

InChI Key

SGFZBLPBUFSDEC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06733493

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

361.47

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.702

Distribution Coefficient, logD

5.701

Water Solubility, LogSw

-5.52

Polar Surface Area

26.296

Acid Dissociation Constant (pKa)

24.95

Base Dissociation Constant (pKb)

4.45

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

G786-2203 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G786-2203 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G786-2203?
Check Price and Availability of G786-2203, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G786-2203 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G786-2203
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G786-2203
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G786-2203 available by request