G786-2375 Screening compound: (2E)-N-[6-acetyl-3-(1,3-benzothiazol-2-yl)-4H,5H,6H,7H-thieno[2,3-c]pyridin-2-yl]-3-(thiophen-2-yl)prop-2-enamide

G786-2375 Screening compound: (2E)-N-[6-acetyl-3-(1,3-benzothiazol-2-yl)-4H,5H,6H,7H-thieno[2,3-c]pyridin-2-yl]-3-(thiophen-2-yl)prop-2-enamide
G786-2375 Screening compound: (2E)-N-[6-acetyl-3-(1,3-benzothiazol-2-yl)-4H,5H,6H,7H-thieno[2,3-c]pyridin-2-yl]-3-(thiophen-2-yl)prop-2-enamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G786-2375
(2E)-N-[6-acetyl-3-(1,3-benzothiazol-2-yl)-4H,5H,6H,7H-thieno[2,3-c]pyridin-2-yl]-3-(thiophen-2-yl)prop-2-enamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G786-2375

Molecular Formula

C23H19N3O2S3 (C23 H19 N3 O2 S3)

Compound Name

(2E)-N-[6-acetyl-3-(1,3-benzothiazol-2-yl)-4H,5H,6H,7H-thieno[2,3-c]pyridin-2-yl]-3-(thiophen-2-yl)prop-2-enamide

IUPAC name

(2E)-N-[6-acetyl-3-(13-benzothiazol-2-yl)-4H5H6H7H-thieno[23-c]pyridin-2-yl]-3-(thiophen-2-yl)prop-2-enamide

SMILES

CC(N(CC1)Cc2c1c(-c1nc(cccc3)c3s1)c(NC(/C=C/c1cccs1)=O)s2)=O

InChI

InChI=1S/C23H19N3O2S3/c1-14(27)26-11-10-16-19(13-26)31-23(25-20(28)9-8-15-5-4-12-29-15)21(16)22-24-17-6-2-3-7-18(17)30-22/h2-9,12H,10-11,13H2,1H3,(H,25,28)

InChI Key

FXGYTJWGLCQDSB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04428059

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

465.62

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.731

Distribution Coefficient, logD

4.725

Water Solubility, LogSw

-4.56

Polar Surface Area

50.427

Acid Dissociation Constant (pKa)

9.24

Base Dissociation Constant (pKb)

1.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

G786-2375 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

DGK Inhibitors Library (10558 compounds)

Eccentric PPI Library (11937 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with G786-2375 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G786-2375?
Check Price and Availability of G786-2375, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G786-2375 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G786-2375
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G786-2375
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G786-2375 available by request