G788-0343 Screening compound: 2-{[3-(4-fluorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]sulfanyl}-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide

G788-0343 Screening compound: 2-{[3-(4-fluorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]sulfanyl}-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide
G788-0343 Screening compound: 2-{[3-(4-fluorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]sulfanyl}-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G788-0343
2-{[3-(4-fluorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]sulfanyl}-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G788-0343

Molecular Formula

C25H23FN4OS (C25 H23 FN4 OS)

Compound Name

2-{[3-(4-fluorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]sulfanyl}-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide

IUPAC name

2-{[3-(4-fluorophenyl)-5-methylpyrazolo[15-a]pyrimidin-7-yl]sulfanyl}-N-(1234-tetrahydronaphthalen-1-yl)acetamide

SMILES

Cc(cc(n1nc2)SCC(NC(CCC3)c4c3cccc4)=O)nc1c2-c(cc1)ccc1F

InChI

InChI=1S/C25H23FN4OS/c1-16-13-24(30-25(28-16)21(14-27-30)18-9-11-19(26)12-10-18)32-15-23(31)29-22-8-4-6-17-5-2-3-7-20(17)22/h2-3,5,7,9-14,22H,4,6,8,15H2,1H3,(H,29,31)/t22-/m0/s1

InChI Key

POQSWQWCKIHGGR-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD27157953

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.55

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.032

Distribution Coefficient, logD

5.028

Water Solubility, LogSw

-4.54

Polar Surface Area

44.239

Acid Dissociation Constant (pKa)

12.25

Base Dissociation Constant (pKb)

5.40

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

24.00

G788-0343 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Angiogenesis library (14822 compounds)

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system

References: we are preparing a list of scientific research reports with G788-0343 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G788-0343?
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What is the minimum amount of G788-0343 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G788-0343
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G788-0343
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G788-0343 available by request