G808-0786 Screening compound: N-[5-chloro-2-({2-methyl-7-oxo-7H-[1,2]oxazolo[2,3-a]pyrimidin-5-yl}methoxy)phenyl]adamantane-1-carboxamide

G808-0786 Screening compound: N-[5-chloro-2-({2-methyl-7-oxo-7H-[1,2]oxazolo[2,3-a]pyrimidin-5-yl}methoxy)phenyl]adamantane-1-carboxamide
G808-0786 Screening compound: N-[5-chloro-2-({2-methyl-7-oxo-7H-[1,2]oxazolo[2,3-a]pyrimidin-5-yl}methoxy)phenyl]adamantane-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G808-0786
N-[5-chloro-2-({2-methyl-7-oxo-7H-[1,2]oxazolo[2,3-a]pyrimidin-5-yl}methoxy)phenyl]adamantane-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G808-0786

Molecular Formula

C25H26ClN3O4 (C25 H26 ClN3 O4)

Compound Name

N-[5-chloro-2-({2-methyl-7-oxo-7H-[1,2]oxazolo[2,3-a]pyrimidin-5-yl}methoxy)phenyl]adamantane-1-carboxamide

IUPAC name

(3R5S7s)-N-[5-chloro-2-({2-methyl-7-oxo-7H-[12]oxazolo[23-a]pyrimidin-5-yl}methoxy)phenyl]adamantane-1-carboxamide

SMILES

CC(ON12)=CC2=NC(COc(ccc(Cl)c2)c2NC(C2(C[C@H](C3)C4)C[C@H]4C[C@H]3C2)=O)=CC1=O

InChI

InChI=1S/C25H26ClN3O4/c1-14-4-22-27-19(9-23(30)29(22)33-14)13-32-21-3-2-18(26)8-20(21)28-24(31)25-10-15-5-16(11-25)7-17(6-15)12-25/h2-4,8-9,15-17H,5-7,10-13H2,1H3,(H,28,31)

InChI Key

LGWFXYNBOSFZCZ-UHFFFAOYSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

467.95

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.702

Distribution Coefficient, logD

4.650

Water Solubility, LogSw

-4.81

Polar Surface Area

68.443

Acid Dissociation Constant (pKa)

8.29

Base Dissociation Constant (pKb)

3.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

48.00

G808-0786 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G808-0786 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G808-0786?
Check Price and Availability of G808-0786, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G808-0786 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G808-0786
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G808-0786
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G808-0786 available by request