G809-0230 Screening compound: 2-{4-[bis(4-fluorophenyl)methyl]piperazin-1-yl}quinoline-4-carboxylic acid

G809-0230 Screening compound: 2-{4-[bis(4-fluorophenyl)methyl]piperazin-1-yl}quinoline-4-carboxylic acid
G809-0230 Screening compound: 2-{4-[bis(4-fluorophenyl)methyl]piperazin-1-yl}quinoline-4-carboxylic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound G809-0230
2-{4-[bis(4-fluorophenyl)methyl]piperazin-1-yl}quinoline-4-carboxylic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G809-0230

Molecular Formula

C27H23F2N3O2 (C27 H23 F2 N3 O2)

Compound Name

2-{4-[bis(4-fluorophenyl)methyl]piperazin-1-yl}quinoline-4-carboxylic acid

IUPAC name

2-{4-[bis(4-fluorophenyl)methyl]piperazin-1-yl}quinoline-4-carboxylic acid

SMILES

OC(c1cc(N(CC2)CCN2C(c(cc2)ccc2F)c(cc2)ccc2F)nc2ccccc12)=O

InChI

InChI=1S/C27H23F2N3O2/c28-20-9-5-18(6-10-20)26(19-7-11-21(29)12-8-19)32-15-13-31(14-16-32)25-17-23(27(33)34)22-3-1-2-4-24(22)30-25/h1-12,17,26H,13-16H2,(H,33,34)

InChI Key

KXXGCLXNPIULCK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27162577

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

459.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.173

Distribution Coefficient, logD

2.725

Water Solubility, LogSw

-5.95

Polar Surface Area

42.455

Acid Dissociation Constant (pKa)

4.54

Base Dissociation Constant (pKb)

4.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.50

G809-0230 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiviral Library (67538 compounds)

CNS Targets (44014 compounds)

DGK Inhibitors Library (10558 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G809-0230 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G809-0230?
Check Price and Availability of G809-0230, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G809-0230 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G809-0230
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G809-0230
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G809-0230 available by request