G810-0143 Screening compound: 2-fluoro-N-[(1-propanoyl-2,3-dihydro-1H-indol-5-yl)methyl]benzene-1-sulfonamide

G810-0143 Screening compound: 2-fluoro-N-[(1-propanoyl-2,3-dihydro-1H-indol-5-yl)methyl]benzene-1-sulfonamide
G810-0143 Screening compound: 2-fluoro-N-[(1-propanoyl-2,3-dihydro-1H-indol-5-yl)methyl]benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G810-0143
2-fluoro-N-[(1-propanoyl-2,3-dihydro-1H-indol-5-yl)methyl]benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G810-0143

Molecular Formula

C18H19FN2O3S (C18 H19 FN2 O3 S)

Compound Name

2-fluoro-N-[(1-propanoyl-2,3-dihydro-1H-indol-5-yl)methyl]benzene-1-sulfonamide

IUPAC name

2-fluoro-N-[(1-propanoyl-23-dihydro-1H-indol-5-yl)methyl]benzene-1-sulfonamide

SMILES

CCC(N(CC1)c2c1cc(CNS(c(cccc1)c1F)(=O)=O)cc2)=O

InChI

InChI=1S/C18H19FN2O3S/c1-2-18(22)21-10-9-14-11-13(7-8-16(14)21)12-20-25(23,24)17-6-4-3-5-15(17)19/h3-8,11,20H,2,9-10,12H2,1H3

InChI Key

DCVYEPOFRZWZGL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27162653

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

362.42

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.822

Distribution Coefficient, logD

2.822

Water Solubility, LogSw

-3.49

Polar Surface Area

57.420

Acid Dissociation Constant (pKa)

10.51

Base Dissociation Constant (pKb)

1.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

G810-0143 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Anti-Inflammatory Library (24602 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Immune system
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G810-0143 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G810-0143?
Check Price and Availability of G810-0143, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G810-0143 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G810-0143
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G810-0143
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G810-0143 available by request