G810-0461 Screening compound: N-{[1-(4-chlorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-4-ethylbenzene-1-sulfonamide

G810-0461 Screening compound: N-{[1-(4-chlorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-4-ethylbenzene-1-sulfonamide
G810-0461 Screening compound: N-{[1-(4-chlorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-4-ethylbenzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G810-0461
N-{[1-(4-chlorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-4-ethylbenzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G810-0461

Molecular Formula

C24H23ClN2O3S (C24 H23 ClN2 O3 S)

Compound Name

N-{[1-(4-chlorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-4-ethylbenzene-1-sulfonamide

IUPAC name

N-{[1-(4-chlorobenzoyl)-23-dihydro-1H-indol-5-yl]methyl}-4-ethylbenzene-1-sulfonamide

SMILES

CCc(cc1)ccc1S(NCc(cc1)cc(CC2)c1N2C(c(cc1)ccc1Cl)=O)(=O)=O

InChI

InChI=1S/C24H23ClN2O3S/c1-2-17-3-10-22(11-4-17)31(29,30)26-16-18-5-12-23-20(15-18)13-14-27(23)24(28)19-6-8-21(25)9-7-19/h3-12,15,26H,2,13-14,16H2,1H3

InChI Key

ZICIFIZYICZLGY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27162786

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

454.98

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.411

Distribution Coefficient, logD

5.411

Water Solubility, LogSw

-5.90

Polar Surface Area

57.676

Acid Dissociation Constant (pKa)

10.51

Base Dissociation Constant (pKb)

-0.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.80

G810-0461 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G810-0461 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G810-0461?
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What is the minimum amount of G810-0461 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G810-0461
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G810-0461
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G810-0461 available by request