G811-1365 Screening compound: 5-[1-(4-chlorophenyl)-1H,2H,3H,4H,9H-pyrido[3,4-b]indole-2-carbonyl]-1-methyl-1H-pyrazole

G811-1365 Screening compound: 5-[1-(4-chlorophenyl)-1H,2H,3H,4H,9H-pyrido[3,4-b]indole-2-carbonyl]-1-methyl-1H-pyrazole
G811-1365 Screening compound: 5-[1-(4-chlorophenyl)-1H,2H,3H,4H,9H-pyrido[3,4-b]indole-2-carbonyl]-1-methyl-1H-pyrazole alternative view

Chemical Structure Depiction of ChemDiv screening compound G811-1365
5-[1-(4-chlorophenyl)-1H,2H,3H,4H,9H-pyrido[3,4-b]indole-2-carbonyl]-1-methyl-1H-pyrazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G811-1365

Molecular Formula

C22H19ClN4O (C22 H19 ClN4 O)

Compound Name

5-[1-(4-chlorophenyl)-1H,2H,3H,4H,9H-pyrido[3,4-b]indole-2-carbonyl]-1-methyl-1H-pyrazole

IUPAC name

5-[1-(4-chlorophenyl)-1H2H3H4H9H-pyrido[34-b]indole-2-carbonyl]-1-methyl-1H-pyrazole

SMILES

Cn1nccc1C(N(CCc1c2[nH]c3c1cccc3)C2c(cc1)ccc1Cl)=O

InChI

InChI=1S/C22H19ClN4O/c1-26-19(10-12-24-26)22(28)27-13-11-17-16-4-2-3-5-18(16)25-20(17)21(27)14-6-8-15(23)9-7-14/h2-10,12,21,25H,11,13H2,1H3/t21-/m1/s1

InChI Key

LBIJGVYWACCSBD-OAQYLSRUSA-N

MDL Number (MFCD)

MFCD27162980

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

390.87

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.016

Distribution Coefficient, logD

4.016

Water Solubility, LogSw

-4.73

Polar Surface Area

39.722

Acid Dissociation Constant (pKa)

18.36

Base Dissociation Constant (pKb)

1.75

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

18.20

G811-1365 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

DGK Inhibitors Library (10558 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Agro:
  • Agro
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with G811-1365 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G811-1365?
Check Price and Availability of G811-1365, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G811-1365 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G811-1365
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G811-1365
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G811-1365 available by request