G812-1983 Screening compound: N-[(2-chlorophenyl)methyl]-4-{3-[(4-methylphenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}butanamide

G812-1983 Screening compound: N-[(2-chlorophenyl)methyl]-4-{3-[(4-methylphenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}butanamide
G812-1983 Screening compound: N-[(2-chlorophenyl)methyl]-4-{3-[(4-methylphenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G812-1983
N-[(2-chlorophenyl)methyl]-4-{3-[(4-methylphenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G812-1983

Molecular Formula

C25H25ClN4O (C25 H25 ClN4 O)

Compound Name

N-[(2-chlorophenyl)methyl]-4-{3-[(4-methylphenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}butanamide

IUPAC name

N-[(2-chlorophenyl)methyl]-4-{3-[(4-methylphenyl)methyl]-3H-imidazo[45-b]pyridin-2-yl}butanamide

SMILES

Cc1ccc(Cn2c(nccc3)c3nc2CCCC(NCc(cccc2)c2Cl)=O)cc1

InChI

InChI=1S/C25H25ClN4O/c1-18-11-13-19(14-12-18)17-30-23(29-22-8-5-15-27-25(22)30)9-4-10-24(31)28-16-20-6-2-3-7-21(20)26/h2-3,5-8,11-15H,4,9-10,16-17H2,1H3,(H,28,31)

InChI Key

BCRCKERZRLKJRA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15038503

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.95

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.695

Distribution Coefficient, logD

4.694

Water Solubility, LogSw

-4.63

Polar Surface Area

45.250

Acid Dissociation Constant (pKa)

13.01

Base Dissociation Constant (pKb)

4.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

G812-1983 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G812-1983 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G812-1983?
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What is the minimum amount of G812-1983 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G812-1983
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G812-1983
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G812-1983 available by request