G812-2146 Screening compound: 1-(4-{3-[(4-fluorophenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}butanoyl)piperidine-4-carboxamide

G812-2146 Screening compound: 1-(4-{3-[(4-fluorophenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}butanoyl)piperidine-4-carboxamide
G812-2146 Screening compound: 1-(4-{3-[(4-fluorophenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}butanoyl)piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G812-2146
1-(4-{3-[(4-fluorophenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}butanoyl)piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G812-2146

Molecular Formula

C23H26FN5O2 (C23 H26 FN5 O2)

Compound Name

1-(4-{3-[(4-fluorophenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}butanoyl)piperidine-4-carboxamide

IUPAC name

1-(4-{3-[(4-fluorophenyl)methyl]-3H-imidazo[45-b]pyridin-2-yl}butanoyl)piperidine-4-carboxamide

SMILES

NC(C(CC1)CCN1C(CCCc1nc2cccnc2n1Cc(cc1)ccc1F)=O)=O

InChI

InChI=1S/C23H26FN5O2/c24-18-8-6-16(7-9-18)15-29-20(27-19-3-2-12-26-23(19)29)4-1-5-21(30)28-13-10-17(11-14-28)22(25)31/h2-3,6-9,12,17H,1,4-5,10-11,13-15H2,(H2,25,31)

InChI Key

XWOTZPMEACDGJQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15038576

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

423.49

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.603

Distribution Coefficient, logD

1.603

Water Solubility, LogSw

-1.87

Polar Surface Area

71.230

Acid Dissociation Constant (pKa)

14.92

Base Dissociation Constant (pKb)

4.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.10

G812-2146 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Proteases
  • Kinases

References: we are preparing a list of scientific research reports with G812-2146 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G812-2146?
Check Price and Availability of G812-2146, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G812-2146 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G812-2146
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G812-2146
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G812-2146 available by request