G812-2221 Screening compound: 4-{3-[(4-fluorophenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}-N-(4-methylphenyl)butanamide

G812-2221 Screening compound: 4-{3-[(4-fluorophenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}-N-(4-methylphenyl)butanamide
G812-2221 Screening compound: 4-{3-[(4-fluorophenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}-N-(4-methylphenyl)butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G812-2221
4-{3-[(4-fluorophenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}-N-(4-methylphenyl)butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G812-2221

Molecular Formula

C24H23FN4O (C24 H23 FN4 O)

Compound Name

4-{3-[(4-fluorophenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}-N-(4-methylphenyl)butanamide

IUPAC name

4-{3-[(4-fluorophenyl)methyl]-3H-imidazo[45-b]pyridin-2-yl}-N-(4-methylphenyl)butanamide

SMILES

Cc(cc1)ccc1NC(CCCc1nc2cccnc2n1Cc(cc1)ccc1F)=O

InChI

InChI=1S/C24H23FN4O/c1-17-7-13-20(14-8-17)27-23(30)6-2-5-22-28-21-4-3-15-26-24(21)29(22)16-18-9-11-19(25)12-10-18/h3-4,7-15H,2,5-6,16H2,1H3,(H,27,30)

InChI Key

UCUGRPOOSZNSRF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15038627

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

402.47

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.241

Distribution Coefficient, logD

4.241

Water Solubility, LogSw

-4.27

Polar Surface Area

43.928

Acid Dissociation Constant (pKa)

12.40

Base Dissociation Constant (pKb)

4.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.80

G812-2221 in Drug Discovery

Included in Screening Libraries

Cardiovascular Library (22201 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G812-2221 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G812-2221?
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What is the minimum amount of G812-2221 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G812-2221
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G812-2221
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G812-2221 available by request